Woman and Man
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Extract
Phase 1 Part: To determine the dose limiting toxicity (DLT) and the maximum tolerated dose (MTD) of cabazitaxel as a single agent in pediatric patients with recurrent or refractory solid tumors including tumors of the central nervous system. Phase 2 Part: To determine the objective response rate (complete and partial response) and the duration of response to cabazitaxel as a single agent in patients with recurrent or refractory high grade glioma (HGG) or diffuse intrinsic pontine glioma (DIPG).
Inclusion criteria
- Cancer