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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche par promoteur : Merck
Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp
MAJ Il y a 4 ans
A Phase III, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy, Safety and Tolerability of a Single Infusion of MK-6072 , and MK-3415A in Patients Receiving Antibiotic Therapy for C. difficile Infection (MODIFY II) Estudio de fase III aleatorizado, doble ciego y controlado con placebo, de la eficacia, la seguridad y la tolerabilidad de una sola infusión de MK-6072 y MK-3415A en pacientes sometidos a tratamiento antibiótico por infección por C. difficile (MODIFY II)
Primary Objective 1: To determine if treatment with a single infusion of monoclonal antibody therapy with SOC therapy (combined monoclonal antibody therapy [MK-3415A] or the individual monoclonal anti...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Generics [UK] Ltd trading as Merck Generics
MAJ Il y a 4 ans
A two-way crossover, sequential-dose, double-blinded, double-dummy, multiple dose, pharmacodynamic, comparative study of fluticasone propionate, 500 μg and 1000 μg twice daily delivered via pressurized metered dose inhaler versus Flixotide®, 500 μg and 1000 μg twice daily delivered via pressurized metered dose inhaler in patients with mild stable asthma
To find out if the study medicine (a generic formulation of fluticasone propionate) is as safe as Flixotide, by measuring their effects on blood and urine levels of cortisol (a steroid produced by the...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Audrey Merckx, MD
MAJ Il y a 4 ans
Evaluation of the Ability to Diagnose the Position of the Intubation Probe Thanks to Lung Ultrasonography
The purpose of this study is to evaluate the diagnostic qualities of lung ultrasonography to monitor the position of the intubation probe. The primary assessment criterion is of study the...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 4 ans
A Phase III, Randomized, Double-blind Study to Evaluate Chemotherapy plus Pembrolizumab vs Chemotherapy plus Placebo as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy for Triple Negative Breast Cancer (TNBC)
1. To evaluate the rate of pCR using the definition of ypT0/Tis ypN0 (i.e., no invasive residual in breast or nodes; noninvasive breast residuals allowed) as assessed by the local pathologist at the ...
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unknown
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Femme et Homme
Entre 18 ans
et 99 ans
Merck Sharp & Dohme (MSD)
MAJ Il y a 4 ans
Étude MK-3475-654 : étude de phase 3 randomisée comparant l’efficacité du pembrolizumab associé à l’épacadostat avec celle du pembrolizumab associé à un placebo chez des patients ayant un cancer du poumon non à petites cellules, métastatique et exprimant fortement PD-L1. [essai clos aux inclusions]
Le cancer du poumon non à petites cellules est le type de cancer du poumon le plus fréquent, représentant 85 à 90 % de l’ensemble des cancers du poumon. Certaines cellules cancéreuses ont la capacité...
Pays
France
Organes
Poumon, type non à petites cellules
Spécialités
Immunothérapie - Vaccinothérapie
Essai clos aux inclusions
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp
MAJ Il y a 4 ans
Study to Evaluate the Safety, Tolerability, and Efficacy of MK-5172 When Administered Concomitantly with Pegylated-Interferon and Ribavirin in Patients with Chronic Genotype 2 or 3 Hepatitis C Virus Infection. Studio volto alla valutazione della sicurezza, della tollerabilita' e dell'efficacia di MK-5172 somministrato in associazione con interferone pegilato e ribavirina, in pazienti con infezione cronica da virus dell'epatite C di genotipo 2 o 3
1. To evaluate the antiviral activity in each of the three arms of MK-5172 (Arms 1, 2, 3) administered in combination with Peg-IFN alfa-2b and RBV as assessed by the proportion of patients achieving u...
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 4 ans
A clinical research study to test the safety/tolerability and effectiveness of an investigational study medication (subcutaneous SCH 900222/MK-3222) in improving the signs and symptoms of moderate-to-severe chronic plaque psoriasis, and to compare it to an approved medication for the treatment of psoriasis called etanercept
Primary Efficacy Objective: To assess the efficacy of SCH 900222/MK-3222, hereafter referred to as MK-3222, compared to placebo in the treatment of moderate-to-severe chronic plaque psoriasis as measu...
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unknown
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 4 ans
Oral MK8669 in Children/Adolescents with Solid Tumors (6-17 years)
• To identify the dose limiting toxicities (DLT) and maximum tolerated dose (MTD) of ridaforolimus when administered to children from 6 to less than 18 years of age with advanced solid tumours. • To...
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unknown
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 4 ans
A Study of Boceprevir in Patients who have HIV and Hepatitis C
The primary objective of this study is to compare the efficacy of boceprevir (PO) in combination with peginterferon alfa-2b (PEG2b) (SC) plus ribavirin weight-based dosing (WBD) PO to therapy with PEG...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Lda. (Portugal)
MAJ Il y a 4 ans
Prospective Randomised comparison of Off-pump and on-pump MultIvessel coronary artery bypasS Surgery: analysis of early graft patency by multi-slice computed tomography
Not provided at time of registration
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