DELTA : Essai de phase 2 évaluant l’efficacité et la tolérance du CAL-101, chez des patients ayant un lymphome non hodgkinien indolent à cellules B, réfractaire au rituximab et aux agents alkylants. [essai clos aux inclusions] L’objectif de cet essai est d’évaluer l’efficacité et la tolérance du CAL-101, chez des patients ayant un lymphome non hodgkinien indolent à cellules B, réfractaire au rituximab et aux agents alkylant...

• Pays France
• Organes Lymphomes non hodgkinien
• Spécialités Thérapies Ciblées

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of 48 Weeks of GS-9190 in Combination with Peginterferon Alfa 2a (Pegasys®) and Ribavirin (Copegus®) in Previously Untreated Subjects with Genotype-1 Chronic Hepatitis C Virus (HCV) Infection To compare the antiviral efficacy (sustained virologic response; SVR) of 48 weeks of GS-9190 versus placebo when administered in combination with 48 weeks of peginterferon alfa 2a (PEG) and ribavirin...

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A study to investigate a new drug to treat Type 2 Diabetes The primary objective of this study is to: • Determine the effect of ranolazine monotherapy on HbA1c in subjects with T2DM who are inadequately controlled with diet and exercise alone and who are t...

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A trial looking at the treatment of SOF/GS-5816 in patients with hepatitis C infection - To evaluate the efficacy of treatment with SOF/GS-5816 for 12 weeks in subjects with chronic HCV infection as measured by the proportion of subjects with SVR12 - To evaluate the safety and tolera...

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A Phase 2 clinical trial investigating the anti-virus effects, kinetics and safety of GS-5806 in adults with RSV (Respiratory Syncytial Virus) infection To evaluate the effect of GS-5806 on RSV viral load in RSV-positive autologous or allogeneic HCT recipients with acute URTI symptoms

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A Phase 2, Randomized, Double-Blind Study Exploring the Efficacy, Safety and Tolerability of Tenofovir Disoproxil Fumarate (DF) Monotherapy Versus Emtricitabine plus Tenofovir DF Fixed-Dose Combination Therapy in Subjects Currently Being Treated with Adefovir Dipivoxil for Chronic Hepatitis B and having Persistent Viral Replication. Estudio aleatorizado de fase 2 a doble ciego para evaluar la eficacia, seguridad y tolerabilidad de la monoterapia de tenofovir disoproxil fumarato (DF) en comparación con la terapia combinada de emtricitabina más tenofovir DF a dosis fija, en pacientes que reciben adefovir dipivoxil en la actualidad para el tratamiento de la hepatitis B crónica y presentan replicación viral persistente To characterize the antiviral activity of tenofovir DF 300 mg QD versus emtricitabine 200 mg/tenofovir DF 300 mg QD in subjects currently being treated with adefovir dipivoxil for CHB who have persist...

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A study comparing 3 different treatments and treatment durations for hepatitis C The primary objectives of this study are: - To determine the efficacy of sofosbuvir (SOF)+ Ribavirin (RBV) for 16 or 24 weeks as measured by the proportion of subjects with sustained viral response 12...

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A Phase 2 clinical trial investigating GS-5806 in adult Lung Transplant (LT) recipients with Respiratory Syncytial Virus (RSV) Infection The primary objective of this study is to evaluate the effect of presatovir (GS-5806) on nasal RSV viral load in RSV-positive LT recipients with acute respiratory symptoms

• Pays Aucun
• Organes Aucun
• Spécialités Aucune

A Double-blind, Randomized, Placebo-controlled Phase 1/2 Study of the Safety, Pharmacokinetics, and Antiviral Activity of GS-9131 in Antiretroviral-Naive, HIV-1 Infected Subjects To investigate the safety, tolerability, and antiviral activity of GS-9131 administered orally as ten consecutive once-daily doses in antiretroviral-naive subjects chronically infected with HIV-1.

• Pays Aucun
• Organes Aucun
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A trial investigating the safety and efficacy of a drug combination Sofosbuvir/Velpatasvir for Subjects with hepatitis C who are on dialysis for kidney disease • To evaluate the antiviral efficacy of treatment with sofosbuvir/velpatasvir (SOF/VEL) for 12 weeks as measured by the proportion of subjects with sustained viral response 12 weeks after cessation of...

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