Phase ll Trial of Fludarabine & Cyclophosphamide followed by Thalidomide for Angioimmunoblastic Lymphoma To assess the response rate of patients treated with FluCy (Fludarabine and cyclophosphamide) chemptherapy.

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A randomised controlled phase III trial comparing hyperthermia plus mitomycin to a second course of bacillus Calmette-Guerin or standard therapy in patients with recurrence of non-muscle invasive bladder cancer following induction or maintenance bacillus Calmette-Guerin therapy The aim of the trial is to determine whether Hyperthermia plus the chemotherapy drug mitomycin is an effective therapy for patients with non-muscle invasive bladder cancer who have tumour recurrence f...

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Ketogenic diet treatment of epilepsy in infants To determine the effectiveness on seizure control of the ketogenic diet (KD) compared to further anti-epileptic drug (AED) treatment in children with epilepsy aged 3 months to 2 years who have failed ...

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Barrett’s oesophagus surveillance with optical biopsy using spectroscopy and enhanced endoscopic imaging to target high-risk lesions Background and study aims An endoscopy is a procedure where the inside of the body is examined using an endoscope - a long, thin, flexible tube that has a light source and a video camera at one end. ...

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Developing an app to help young people self-manage when feeling overwhelmed during lessons Background and study aims In England, between 3-7% of school aged children experience behavioural difficulties. Behavioural difficulties can have a negative long-term impact. For example, evidence sho...

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Phase II study of Bortezomib, Adriamycin and Dexamethasone (PAD) therapy for previously untreated patients with multiple myeloma: Impact of minimal residual disease (MRD) in patients with deferred ASCT (PADIMAC) What is the 2-year progression-free survival (PFS) for patients who, having achieved CR/VGPR following PAD therapy, do not receive any further treatment until clinical indication of relapse? This que...

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Emotional stimulation as a cost-effective addition to emergency food intervention for malnutrition in a low income country Background and study aims East Africa is suffering from devastating droughts and, in Ethiopia, it is estimated that there are 652,000 malnourished children under the age of five in need of emergency ...

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A feasibility study of patient navigation in bowel scope screening http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-study-looking-at-a-way-to-support-people-as-they-make-a-decision-to-have-bowel-scope-screening

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Intraoperative hypotension in elder patients (IHypE) Background and study aims Low blood pressure during surgery (also known as intraoperative hypotension or IOH) is thought to be very common. It happens as a side effect of the medicines used during ana...

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Depletion of serum Amyloid P Component in Alzheimer's Disease Background and study aims: Alzheimer’s disease (AD) is the most common cause of dementia, affecting around 30 million individuals worldwide. It is caused by the abnormal build-up of various proteins i...

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