Expressive writing intervention for body image concerns http://cancerhelp.cancerresearchuk.org/trials/a-study-writing-experience-women-after-surgery-breast-cancer

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UK GRACE Risk Score Intervention Study Background and study aims Acute coronary syndrome (ACS) refers to a group of conditions due to decreased blood flow in the coronary arteries such that part of the heart muscle is unable to function pr...

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Stratification of patellofemoral pain (StrOPP) Background and study aims Patellofemoral pain (PFP) is a common cause of pain in the region of the kneecap that is not related to any other injury or condition. Recent evidence suggests that 1 in 6 ad...

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Pain reduction with oral methotrexate in knee osteoarthritis Not provided at time of registration

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Measuring omega-3 fatty acid levels in terminal ileal content following four weeks of omega-3 fatty acid supplementation in patients with a temporary ileostomy Background and study aims Oily fish such as mackerel and sardines contain natural omega-3 fatty acids (O3FAs). They are commonly used as nutritional supplements in capsule form, with evidence suggesti...

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Treating painful hand osteoarthritis using low dose oral prednisolone- assessing short-term pain and imaging outcomes This is a randomised, double blind, placebo controlled trial to compare the effectiveness of prednisolone versus placebo in a group of patients with painful hand osteoarthritis. Primary outcome is th...

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Pressure RElieving Support SUrfaces: a Randomised Evaluation 2 Background and study aims The development of pressure ulcers (PUs) in patients staying in hospital is a significant problem in the NHS. Preventive measures include the use of an array of mattress type...

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The effect of monetary deposits on weight loss, specifically the effect of monetary deposits that are refunded contingent on weight loss of an individual and a 'weight loss partner' Background and study aims: Over half of the adults in the UK are overweight or obese and these numbers are expected to increase even further. As obesity often leads to serious health problems such...

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A phase II randomised trial of carfilzomib, cyclophosphamide and dexamethasone (CCD) compared to cyclophosphamide, velcade and dexamethasone (CVD)for first relapse or primary refractory mutiple myeloma patients To compare the activity of carfilzomib in combination with cyclophosphamide and low dose dexamethasone (CCD) to that of the control treatment of bortezomib, cyclophosphamide and dexamethasone (CVD) in...

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SHIFT Trial - Family therapy vs treatment as usual for young people seen after second or subsequent episodes of self-harm Background and study aims The main aim of this study is to assess the effectiveness of Family Therapy (FT) compared to Treatment as Usual (TAU) for adolescents aged 11-17 years who have engaged in at ...

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