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Extrait
To assess the pharmacodynamics (PD) of a single oral dose of PSI-697 in healthy subjects who smoke.
Critère d'inclusion
- PSI-697 is an orally active inhibitor of the cellular adhesion molecule P-selectin that offers a unique, first in class mechanism for preventing the vascular atherothrombotic state that is driven by the accumulation leukocytes and platelets in the vascular wall