Prospective Randomized Clinical Trial of Total Thyroidectomy (Tx) versus Anti-Thyroid Drugs (ATD) in Patients with Moderate-to-Severe Graves’ Ophthalmopathy - a 1-year Follow-up

Update Il y a 4 ans
Reference: EUCTR2015-003515-38

Woman and Man

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Extract

To examine the difference in the outcome of GO in patients with moderate-to-severe GO, who receive Tx versus further ATD after suffering their first relapse following the initial decrease in ATD after 6 months. Establish a glucocorticoid scheme before and after Tx in patients with moderate-to-severe EO. The difference will primarily be measured in terms of the Muscle Index score determined through an ultrasound.


Inclusion criteria

  • Graves' disease, hyperthyroidism

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