Woman and Man
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Extract
The primary objective of this study is to assess the efficacy of IV MOA-728 in subjects who have undergone repair of large (³10 cm) ventral hernias, with or without a mesh prosthesis via laparotomy or laparoscopy.
Inclusion criteria
- Post operative ileus (POI). This study will examine the effect of IV MOA-728 versus placebo in shortening the time to return of bowel function in subjects receiving opioid analgesia administered via PCA, who have undergone repair of large (³10 cm, measured from edge to edge in its greatest dimension) ventral hernias with or without a mesh prosthesis