Study of the investigational drug MEHD7945A in comparison to the anticancer drug cetuximab in patients with head and neck cancer that progressed during or after platinum-based chemotherapy

Update Il y a 4 ans
Reference: EUCTR2011-005539-22

Woman and Man

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Extract

This is a phase II, open-label, randomized study of MEHD7945A versus cetuximab in patients with recurrent/metastatic squamous cell carcinoma of the head and neck who have progressed during or following platinum-based chemotherapy. The main objective is to evaluate the efficacy of MEHD7945A (administered every 2 weeks) versus cetuximab (administered weekly) in all and in biomarker positive patients with recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN), as measured by progression-free survival (PFS).


Inclusion criteria

  • Head and neck cancer of squamous cell origin