Marker Evaluation for Avastin Research in colorectal cancer

Mise à jour : Il y a 4 ans
Référence : EUCTR2011-004755-39

Femme et Homme

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Extrait

To assess whether: • Expression of chemotherapy resistance marker ERCC-1 is associated with progression-free survival (PFS) in first-line metastatic colorectal cancer (CRC) patients treated with bevacizumab in combination with mFOLFOX6 or FOLFIRI • Plasma level of vascular endothelial growth factor A (VEGF-A) as a potential biomarker for bevacizumab, and in combination with ERCC-1 expression as a chemotherapy regimen biomarker, is associated with different PFS


Critère d'inclusion

  • Metastatic colorectal cancer