Extrait

Background and study aims Gastric cancer is a common cause of cancer death in Zambia as elsewhere. There are no interventions (treatment) available for prevention which can be applied to an African population. We have observed that over the last 30 years there appears to have been a trend towards diagnosis at a younger age. This study is designed to test the hypothesis that HIV and/or dietary factors (particularly antioxidant intake in the form of fruit and vegetables) might contribute to what appears to be a changing epidemiology. Who can participate? Patients presenting to the endoscopy unit of the University Teaching Hospital, Lusaka, Zambia. What does the study involve? Participants were recruited at the time of endoscopy which has been requested by their physician. If a lesion was seen which is suspicious for gastric cancer, they were recruited if the tests confirmed the diagnosis of gastric cancer. Controls were recruited from patients seen subsequently who have normal endoscopy and are the same sex and in the same age band. What are the possible benefits and risks of participating? The benefits to the individual are minimal except for the additional attention they will receive. The risks are only the inconvenience of answering the questions and submitting blood and urine samples. Where is the study run from? The University Teaching Hospital, Lusaka, Zambia. When is the study starting and how long is it expected to run for? The study started in December 2010 and completed in January 2012. Who is funding the study? National Institutes of Health, USA. Who is the main contact? Dr Paul Kelly [email protected]

Critère d'inclusion

• Gastric Adenocarcinoma

Liens

• isrctn
• ictrp