A Multi-centre, Double-blind, Double-Dummy, Placebo-controlled, Parallel Group, Randomised, Phase IIb Proof of Concept Study with 3 oral dose groups of AZD3480 or donepezil during 12 weeks treatment i...

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Reference: EUCTR2007-000835-24

A Multi-centre, Double-blind, Double-Dummy, Placebo-controlled, Parallel Group, Randomised, Phase IIb Proof of Concept Study with 3 oral dose groups of AZD3480 or donepezil during 12 weeks treatment in patients with Alzheimer’s Disease Estudio en fase IIB, multicéntrico, doble ciego, controlado con placebo, de grupos paralelos y aleatorizado, de tratamiento con 3 dosis orales de AZD3480 o donepezilo durante 12 semanas en pacientes con enfermedad de Alzheimer. Prueba de concepto

Woman and Man

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Extract

To prove the concept that AZD3480 improves cognition in Alzheimer's disease patients in relation to placebo and donepezil, assessed as change from baseline on Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog).


Inclusion criteria

  • Alzheimer's Disease
  • Enfermedad de Alzheimer