HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1 Co-infected Persons Over 80% of HIV-1 infected persons are also seropositive for HSV-2. Increasingly, clinical and epidemiologic evidence show the role of HSV in increasing HIV infectiousness. The evidence su...

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Herpes Simplex Virus Type 2 (HSV-2) Suppression to Prevent HIV Transmission The University of Washington has received funding to conduct a proof-of-concept trial to assess the impact of suppression of genital herpes on HIV infectiousness. This study (the Partners ...

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HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1, HSV-2 Co-infected Men Over 80% of HIV-1 infected persons are also seropositive for HSV-2. Increasingly, clinical and epidemiologic evidence show the role of HSV in increasing HIV infectiousness. The evidence su...

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Strategies to Increase HIV Testing, Linkages to Care, and Male Circumcision in Africa The purpose of this study is to determine efficient, scalable, evidence-based strategies to link HIV positive individuals to care and HIV negative individuals to prevention measures, such ...

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GUD Clinical and Virologic Response to Acyclovir in HIV Negative African Women To examine the time to healing of genital lesion and duration of herpes simplex virus (HSV) shedding from genetic ulcer disease (GUD) among 90 HIV-negative African women who have a history...

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Valacyclovir vs. Acyclovir as HSV-2 Suppressive Therapy: Effect on Plasma HIV-1 Levels Among HIV-1/HSV-2 Co-infected Persons The purpose of this study is to determine whether treating HSV-2 with either valacyclovir or acyclovir is more effective in suppressing HIV-1 virus levels in people co-infected with HIV-1 ...

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