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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche par promoteur : AstraZeneca AB
Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A Phase IIIb, efficacy, and safety study of rosuvastatin in children and adolescents 10 to 17 years of age with heterozygous familial hypercholesterolemia (HeFH): a 12-week, double-blind, randomized, multi-center, placebo-controlled study with a 40-week, open-label, follow-up period
The primary objective of this study is to determine the efficacy of once-daily rosuvastatin in reducing LDL-C in children and adolescents aged 10-17 years with HeFH from baseline (Day 0) to the end of...
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Aucune
unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A Randomised, Double-Blind, Placebo-Controlled, Two-Way Crossover Study in Healthy Volunteers to Investigate the Effect of Oral Dosing with AZD8309 on Airway Inflammation as Assessed in Induced Sputum after Challenge with Inhaled Lipopolysaccharide (LPS)
The primary objective of this study is to investigate the effect of AZD8309 compared to placebo treatment on neutrophil numbers in induced sputum after administration of inhaled LPS.
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unknown
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Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A Single-Centre, Double-blind, Double-dummy, Randomised, Placebo Controlled, Four Period Crossover Study to Assess the Effect of Single Oral Doses of AZD5672 (600mg and 150mg) on QT/QTc Interval, Compared to Placebo, using Moxifloxacin (Avelox®) as a Positive Control, in Healthy Male Volunteers
To evaluate the change in time-matched QTcF intervals of single dose AZD5672 600mg compared to placebo.
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Essai clos aux inclusions
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Femme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A Phase II randomised, double-blind, stratified, multi-centre trial comparing the Nolvadex 20 mg and placebo combination to the Nolvadex 20 mg and ZD1839 (IRESSA™) 250 mg combination in patients with metastatic breast cancer and estrogen receptor (ER) and/or progesterone (PR) positive tumours
Strata 1 To compare the time to progression between 2 treatment arms (ZD1839/Nolvadex vs placebo/Nolvadex ) Strata 2 To compare the clinical benefit rate between 2 treatment arms (ZD1839/Nolvadex ...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
Study of MEDI4736, when used alone or in combination with Tremelimumab, as second line chemotherapy in metastatic Pancreatic Ductal Adenocarcinoma
To assess the efficacy of MEDI4736 monotherapy and MEDI4736 + tremelimumab combination therapy in terms of objective response rate
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
To investigate the safety and tolerability of AZD9291 when given orally to patients with non small cell lung cancer. These patients will be chosen from those who have already been prescribed an EGFR TKI medicine (such as Iressa or Tarceva)
To investigate the safety, tolerability and efficacy (Objective Response Rate) of AZD9291 when given orally to patients with locally advanced or metastatic Non Small Cell Lung Cancer (NSCLC) who have ...
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A 6 month safety study comparing Symbicort with inhaled corticosteroid only in asthmatic adults and adolescents
To evaluate the risk of serious asthma related events during treatment with Symbicort pMDI or budesonide pMDI alone (asthma-related deaths, intubations, hospitalizations).
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Essai clos aux inclusions
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Femme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A Randomised, Double-Blind, Parallel-group, Multicentre, Phase III Study Comparing the Efficacy and Tolerability of Fulvestrant (FASLODEX™) 500 mg with Fulvestrant (FASLODEX™) 250 mg in Postmenopausal Women with Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing after Previous Endocrine Therapy
To compare the efficacy of fulvestrant 500 mg treatment with fulvestrant 250 mg treatment in terms of time to progression (TTP)
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A Pan-European, open label, randomised study comparing the efficacy and cost-effectiveness of Symbicort Maintenance and Reliever Therapy (Symbicort SMART) using a maintenance dose of Symbicort 160/4.5 micrograms of 1 or 2 inhalations twice daily in the treatment of persistent asthma. EUROSMART
To compare efficacy of Symbicort Maintenace and Reliever Therapy (Symbicort SMART) administered over 6 months at two different maintenance doses in adult asthmatic subjects on IGCS: 1 inhalation Symbi...
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
Multicentre, open label, extension study of treatment with gefitinib (IRESSA™) for patients completing other gefitinib clinical studies who may benefit from gefitinib treatment
The primary objective of this study is to provide, or continue to provide, gefitinib treatment to patients who have recently participated in other gefitinib clinical studies.
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Essai clos aux inclusions
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