Electronic cigarettes: Nicotine delivery in users Background and study aims Electronic cigarettes (ECs) are a developing technology that aims to provide nicotine without the harmful chemicals produced by smoking tobacco. ECs have the potential to be...

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Graded Exercise Therapy guided SElf-help Treatment for CFS/ME Background and study aims Chronic fatigue syndrome, also known as myalgic encephalomyelitis (CFS/ME), is a chronic disabling condition of no known cause. It affects about one in a hundred people. Gui...

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The EPOS trial: effective patient-clinician communication in community mental health care Background and study aims Schizophrenia and related disorders are disabling for patients and generate high costs to the NHS and society. At present in Community Mental Health Teams (CMHTs), patients ...

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All-Trans Retinoic acid as an Oral Adjuvant Background and study aims The purpose of this study is to find a way to overcome the poor immune responses to oral vaccines seen in developing countries. We have previously found that all-trans retino...

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Gastric cancer in Zambian adults Background and study aims Gastric cancer is a common cause of cancer death in Zambia as elsewhere. There are no interventions (treatment) available for prevention which can be applied to an African po...

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CONtrol of Faecal Incontinence using Distal NeuromodulaTion Background and study aims Faecal incontinence occurs when a person passes faeces (stools) without the usual control. It is a distressing condition that is actually very common although under-reported ...

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Short-term effects of standard weight management advice and of the 5-2 diet delivered in self-help or group support format Background and study aims The 5:2 diet consists of limiting food intake to 500 calories in women and 600 calories in men on two non-consecutive days per week. The diet became popular with extensive re...

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Response to an invitation to Self-sampling for Human papillomavirus (HPV) versus repeat Invitation for cervical screening in persistent non-responders in NEwcastle upon Tyne Background and study aims The aim of this research study is to find out whether women who have already been invited more than once to attend for a cervical smear test, and have not been for one, would...

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INTERACT Trial Background and study aims Two facts regarding cardiovascular diseases are well established. First, that lowering blood pressure and cholesterol can reduce the risk of heart attacks and strokes to a g...

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Invitation reminder study Background and study aims Breast screening saves lives by detecting cancer earlier, which can make treatment more effective. This reduction in cancer deaths depends partially on women regularly attend...

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