A phase 3 study to determine the efficacy and safety of recombinant human activated protein C in severe sepsis Not provided at time of registration

• Pays Belgium, Canada, France, Spain, United States
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A Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Participants With EGFR Mutation-Positive Metastatic Non-Small Cell Lung Cancer (NSCLC) The primary objective of Part B is to compare the PFS of ramucirumab administered in combination with erlotinib versus placebo in combination with erlotinib in previously untreated patients with EGFR ...

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Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Pemetrexed and Cisplatin plus Enzastaurin versus Pemetrexed and Cisplatin plus Placebo in Chemonaive Patients with Advanced, Unresectable, or Metastatic (Stage IIIB or IV) Nonsquamous Non-Small Cell Lung Cancer The study will be conducted in 2 parts: • Part 1: a single-arm, unblinded, safety lead in. • Part 2: a multiple-site, randomized, double-blind, placebo-controlled study. The objective of the Safety l...

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The Effect of Postprandial Hyperglycemia on Arterial Stiffness in Patients with Type 2 Diabetes to examine in T2DM patients whether pulse wave velocity (PWV) differs between postprandial hyperglycemia and nearly normal postprandial glycemia, and whether microalbuminuria influences the outcome of...

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Duloxetine 60/120 mg Versus Placebo in the Treatment of Fibromyalgia Syndrome to assess the efficacy of duloxetine 60/120mg once daily (QD) compared with placebo on the treatment of pain in patients with American College of Rheumatology (ACR) defined primary fibromyalgia syndro...

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Study of Abemaciclib with Pembrolizumab in Patients with Stage IV Lung Cancer or Breast Cancer To characterize further the safety profile of the combination of abemaciclib and pembrolizumab

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A Study of Soft Tissue Sarcoma with Olaratumab, Gemcitabine and Docetaxel Overall Survival (OS)

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Home Delivery of Pemetrexed : A Feasibility Study To assess the adherence rate to pemetrexed administered in a domiciliary setting.

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A study of blood pressure and pulse rate in type 2 diabetes mellitus The primary objective of this study is to demonstrate that the change from baseline in mean 24 hour systolic blood pressure of LY2409021 20 mg is noninferior to placebo at 6 weeks, as measured by ABPM...

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A Phase 3 Study in Moderate to Severe Psoriasis Patients Efficacy of ixekizumab in subjects with moderate to severe chronic plaque psoriasis based on sPGA and PASI at 12 weeks

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