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Kusajili – Clinical trials directory
Result
of your search per sponsor: F. Hoffmann-La Roche Ltd
Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
Treatment Resistant Depression study for RO4995819
To evaluate the efficacy of 6 weeks treatment of RO4995819 versus placebo as adjunctive therapy in patients with MDD having inadequate response to ongoing antidepressant treatment based on mean change...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
A Study of Pertuzumab in Addition to Chemotherapy and Herceptin (Trastuzumab) as Adjuvant Therapy in Patients With HER2-Positive Primary Breast Cancer
To compare invasive disease-free survival (IDFS) in patients with HER2-positive breast cancer randomized to chemotherapy plus one year of trastuzumab plus placebo or chemotherapy plus one year of tras...
Country
None
organs
None
Specialty
None
unknown
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Woman Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
Randomized phase II study comparing pertuzumab, trastuzumab and an aromatase inhibitor vs. trastuzumab and an aromatase inhibitor in patients with HER2 and ER/PgR positive breast cancer Estudio clínico de fase II, para comparar pertuzumab, trastuzumab e inhibidores de la aromatasa vs trastuzumab e inhibidores de la aromatasa en pacientes con cáncer de mama HER2+ y receptor hormonal positivo
To compare progression-free survival (PFS) of pertuzumab given in combination with trastuzumab plus an aromatase inhibitor (AI) versus trastuzumab plus an AI. Comparar la supervivencia libre de ...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
An open label multi-center trial of oseltamivir for the seasonal prophylaxis of influenza in children
•to evaluate the safety of 6 weeks of seasonal prophylaxis of influenza in children •to evaluate the effect of oseltamivir in preventing laboratory confirmed clinical influenza in children
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Patients with Geographic Atrophy Secondary to Age-Related Macular Degeneration (Study #1)
To evaluate the efficacy and safety of 10 mg lampalizumab intravitreal injections of administered every 4 weeks (Q4W) or every 6 weeks (Q6W) in patients compared with sham control assessed by change i...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
A randomised, double-blind, international study to evaluate the efficacy and safety of various re-treatment regimens of rituximab in combination with methotrexate in RA patients with an inadequate response to methotrexate
1. To determine if a second course with an increased dose of rituximab is associated with improved responses compared to re-treatment with the same dose. 2. To determine if there is a difference in re...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
A comparative study of MPDL3280A versus chemotherapy in patients with advanced bladder cancer
To evaluate the efficacy of MPDL3280A treatment compared with chemotherapy treatment with respect to OS in patients with locally advanced or metastatic UBC who have progressed during or following a pl...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
Estudio en grupos paralelos, de fase II de Tarceva® (Erlotinib) en pacientes con cancer de pulmón no microcítico avanzado (estadios IIIB/IV) no tratados previamente con quimioterapia incluyendo una escalada de dosis hasta toxicidad en ex fumadores y fumadores habituales. A parallel phase II study of Tarceva® (Erlotinib) in patients with advanced non-small cell lung cancer (Stage IIIB/IV) nt pre-treated by chemotherapy including dose escalation to toxicity in current and former smokers
Eficacia de erlotinib administrado como un agente simple en pacientes con CPNM avanzado no tratado previamente con quimioterapia determinado por la Tasa de No Progresión (TNP) a las 8 semanas. La eval...
Country
None
organs
None
Specialty
None
unknown
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Woman Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
A phase II, open- label, controlled, randomized, multicenter study to evaluate the efficacy and safety of pertuzumab (Omnitarg™), a recombinant humanized antibody against HER2, in combination with carboplatin-based standard chemotherapy versus carboplatin-based standard chemotherapy alone in patients with platinum-sensitive recurrent ovarian cancer
To make a preliminary assessment of the efficacy of pertuzumab in combination with carboplatin-based standard chemotherapy as compared to carboplatin-based standard chemotherapy alone, in patients wit...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
A multi-center, double-blind, randomized, placebo-controlled, titration study to investigate the safety, the tolerability and the pharmacodynamic profiles of different doses of RO5073031 in patients with type 2 diabetes mellitus treated with a stable dose of metformin
The primary objective of the study is to evaluate the tolerability of different doses of RO5073031 (30 mg and 40 mg weekly) when administered following injection of 20 mg weekly for 4 weeks to diabeti...
Country
None
organs
None
Specialty
None
Closed trial
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