A Study of MM-111 and Paclitaxel with or without Trastuzumab in patients with Metastatic or Locally Advanced Cancer of the Esophagus, Gastroesophageal Junction and Stomach Estudio de MM-111 y paclitaxel con o sin trastuzumab en pacientes con carcinoma con cáncer de esófago, unión gastroesofágica o estómago con metastástasis o localmente avanzado The primary objective of the study is to compare the Progression Free Survival (PFS) between the experimental and comparator arms within two distinct patient populations: Patients with ?Traditional? ...

• Country None
• organs None
• Specialty None

A phase 2 study comparing MM-302 plus trastuzumab versus Chemotherapy of Physicians Choice plus trastuzumab in HER2+ metastatic breast cancer patients To determine whether the combination of MM-302 plus trastuzumab is more effective than chemotherapy of physician’s choice (CPC) plus trastuzumab based on progression free survival (PFS) as assessed by...

• Country None
• organs None
• Specialty None

Étude SHERLOC MM-121-01-02-09 : étude de phase 2, randomisée, comparant l’efficacité d’un traitement associant le MM-121, un anticorps anti-HER3, au docétaxel ou au pémétrexed à un traitement par docétaxel ou pémétrexed seul, chez des patients ayant un cancer du poumon non à petits cellules localement avancé ou métastatique et présentant un test positif pour l’héréguline. Le cancer du poumon non à petites cellules est le type de cancer du poumon le plus fréquent, qui représente 85-90% de l’ensemble des cancers du poumon. Environ la moitié des patients de cancer du poum...

• Country France
• organs Poumon, type non à petites cellules
• Specialty Chimiothérapie, Immunothérapie - Vaccinothérapie

A study of MM-398 with or without 5-Fluorouracil and Leucovorin compared with 5- Fluorouracil and Leucovorin in Patients with advanced pancreatic cancer who were previously treated unsuccessfully with a gemcitabine-based therapy To compare overall survival following treatment with MM-398, with orwithout 5-fluorouracil and leucovorin,versus 5-fluorouracil and leucovorin in patients with metastatic pancreatic cancer that have ...

• Country None
• organs None
• Specialty None