Rituximab in rheumatoid arthritis: is a reduced dose every 6 months equally effective as the regular dose if the patient has low or very low disease activity? Background and study aims Rheumatoid arthritis (RA) is a long-term disease causing pain, swelling and stiffness in the joints. It is a disease of the immune system, known as an autoimmune disease, in...

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Effects of Oxygen on the human body Effekte von Sauerstoff auf den menschlichen Körper Hyperoxia induces ROS in leucocytes Hyperoxie führt zur ROS Bildung in Leukozyten

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Removal of intestinal colonization with bacteria resistant to many antimicrobial agents by ingestion of a probiotic substance Behandlung einer Besiedelung des Darmes mit multiresistenten Erregern mit Hilfe eines Probiotikums Removal of multi resistant bacteria from the intestine Verdrängung multiresistenter Bakterien aus dem Darm

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Evaluation of the pharmacodynamic effects of riociguat in subjects with pulmonary hypertension and heart failure with preserved ejection fraction in a randomized, double blind, placebo controlled, parallel group, multicenter study Pharmakodynamische Effekte des Medikaments Riociguat (Adempas®) bei Patienten mit Lungenhochdruck in Verbindung mit einer Herzinsuffizienz und erhaltener Linksventrikelfunktion – eine randomisierte, doppelblinde, Placebo kontrollierte, multizentrische Parallellgruppen-Studie The primary objective of this study is to - Assess the pharmacodynamic profile of riociguat in subjects with symptomatic pulmonary hypertension and heart failure with preserved ejection fraction

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Response of retinal vessels to anti vascular endothelial growth factor (VEGF) treatment in patients with branch retinal vein occlusion (BRVO) Main outcome measure: Retinal vessel diameters

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Acetylic salicylic acid for the treatment of Chronic Obstructive Pulmonary Disease (COPD). A randomized, double-blind, placebo-controlled trial To evaluate the effect of ASA as add-on therapy in COPD patients in comparison to placebo in spirometric and clinical regard, and to evaluate safety of this therapy.

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Characterization of Renin-Angiotensin-System at patients with Empagliflozin therapy and Angiotensin-converting enzyme inhibition. Charakterisierung des Renin-Angiotensin-Systems bei Patienten mit Empagliflozin-Therapie und Angiotensin-Converting Enzyme Hemmung The difference of Ang 1-7 increase from baseline between a 3-month treatment with empagliflozin on top of ACEi treatment compared to ACEi treatment alone

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Mesalamine for Colorectal Cancer Prevention Program in Lynch syndrome The primary objective of the study is to test whether 5-ASA reduces the occurrence of colonic benign or malignant neoplasia compared to placebo in LS patients as detected by any colonoscopy until the ...

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Effects of mannitol on kidney function after kidney transplantation Effects of mannitol on delayed graft function after cadaveric renal transplantation

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Larynxmaske bei Kindern nach Atemwegsinfekt: Der Effekt topischer Anästhesie mit Lidocain Effect of Lidocain-gel for laryngeal mask lubrification in pediatric patients after acute respiratory disease Study the effect of topical anesthesia with lidocain gel for laryngeal mask lubrification on perioperative respiratory adverse events in pediatric patients undergoing general anesthesia with or withou...

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