A trial looking at GDC0941 and anastrozole for oestrogen positive breast cancer (OPPORTUNE) http://www.cancerresearchuk.org/cancer-help/trials/a-trial-looking-gdc0941-anastrozole-oestrogen-positive-breast-cancer-opportune ?

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A Study to Assess the Efficacy and Safety of MSTT1041A in Patients with Uncontrolled Severe Asthma • To evaluate the efficacy of MSTT1041A compared with placebo

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Study of the novel cancer drug GDC-0941 in combination with the approved anticancer drug fulvestrant, and the novel cancer drug GDC- 0980 in combination with fulvestrant, in patients with advanced breast cancer for whom treatment with an aromatase inhibitor is not effective •To evaluate the efficacy (as measured by PFS) of fulvestrant + GDC-0941 versus fulvestrant + placebo •To evaluate the safety of fulvestrant+GDC 0941 and fulvestrant + GDC 0980 versus fulvestrant + p...

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A study to evaluate the long term safety of rhuMab Beta7 in patients with moderate to severe ulcerative colitis (a form of inflammatory bowel disease) Estudio para evaluar la seguridad de rhuMab Beta7 a largo plazo en pacientes con colitis ulcerosa moderada o grave (una forma de enfermedad inflamatoria del intestino) To assess the long-term safety and tolerability of rhuMAb Beta7, as measured by adverse events, immunogenicity and safety laboratory parameters, over an extended 2 year treatment period Evaluar ...

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A study of MetMAb in combination with Tarceva administered to patients with non-small cell lung cancer (NSCLC) The primary objective of this study is to determine whether the combination of onartuzumab + erlotinib is superior (in terms of OS) to placebo + erlotinib after standard platinum-based chemotherapy in...

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A Study of DCDT2980S and DCDS4501A Combined with Rituximab in Patients with Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma Safety and tolerability and anti-tumor activity of DCDT2908S combined with Rituximab and DCDS4501A combined with Rituximab.

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Study of the investigational drug MEHD7945A in comparison to the anticancer drug cetuximab in patients with head and neck cancer that progressed during or after platinum-based chemotherapy This is a phase II, open-label, randomized study of MEHD7945A versus cetuximab in patients with recurrent/metastatic squamous cell carcinoma of the head and neck who have progressed during or followin...

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A Study to Explore the Mechanism of Action of Ocrelizumab and B-cell Biology in Patients with Relapsing Multiple Sclerosis • To understand the impact of ocrelizumab treatment on neurofilament light (NfL) as a biomarker of neuronal damage in cerebrospinal fluid (CSF) • To assess the number of cluster of differentiation (C...

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A study to compare the effects of ipatasertib in combination with paclitaxel to placebo in combination with paclitaxel in patients with early stage triple negative breast cancer. ESTUDIO PARA COMPARAR LOS EFECTOS DE IPATASERTIB EN COMBINACIÓN CON PACLITAXEL O PLACEBO EN PACIENTES CON CÁNCER DE MAMA TRIPLENEGATIVO EN ESTADIO INICIAL - To estimate the efficacy of ipatasertib combined with paclitaxel compared with placebo combined with paclitaxel in patients with early stage TNBC, as measured by evaluation of pCR rate within the br...

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A clinical trial of MABT5102A for the treatment of Alzheimer's Disease Un ensayo clínico de MABT5102A para el tratamiento de la Enfermedad de Alzheimer To assess amyloid burden via 18F-florbetapir (18F-AV-45) positron emission tomography (florbetapir-PET) in patients with mild to moderate AD and to evaluate whether treatment with MABT5102A (a monoclo...

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