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Kusajili – Clinical trials directory
Result
of your search per sponsor: Janssen
Woman and Man
Between 18 years
and 99 years
Janssen-Cilag International N.V
Update Il y a 5 ans
CR100956 : Essai de phase 2, évaluant l’efficacité et la tolérance d’une thérapie ciblée, l’ibrutinib (PCI-32765), inhibiteur de la tyrosine kinase de Bruton, chez des patients ayant un lymphome folliculaire réfractaire. [Informations issues du site clinicaltrials.gov et traduites par l'INCa] [essai clos aux inclusions]
L’objectif de cet essai est d’évaluer l’efficacité et la tolérance de l’ibrutinib, chez des patients ayant un lymphome folliculaire réfractaire ou en rechute après deux lignes de traitement. Les pati...
Country
France
organs
Lymphomes non hodgkinien
Specialty
Thérapies Ciblées
Essai clos aux inclusions
More information
Woman and Man Max 99 years
Janssen-Cilag International NV
Update Il y a 5 ans
A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants with Treatment-resistant Depression
The primary objective of this study is to evaluate the efficacy of switching elderly subjects with TRD from a prior antidepressant treatment (to which they have not responded) to flexibly dosed intran...
Country
None
organs
None
Specialty
None
unknown
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Man Max 99 years
Janssen-Cilag International NV
Update Il y a 5 ans
An Efficacy and Safety Study of JNJ56021927 (ARN509) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS
To determine if apalutamide plus gonadotropin releasing hormone (GnRH) agonist in subjects with high-risk, localized or locally advanced prostate cancer receiving primary radiation therapy (RT) result...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Wim Janssens, Prof
Update Il y a 5 ans
Vitamin D as Treatment for Chronic Obstructive Pulmonary Disease (COPD)
This project aims to explore the relationship between Vitamin D deficiency and COPD progression via a prospective randomized placebo-controlled study. For this purpose, study was powered t...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Janssen-Cilag International NV
Update Il y a 5 ans
A Study of Ibrutinib (a Bruton’s Tyrosine Kinase Inhibitor), Versus Temsirolimus in Patients With Relapsed or Refractory Mantle Cell Lymphoma Who Have Received at Least One Prior Therapy
The primary objective of the study is to evaluate whether treatment with ibrutinib compared with temsirolimus will result in prolongation of PFS, as determined by blinded independent central review, i...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Janssen-Cilag International NV
Update Il y a 5 ans
A Safety and Efficacy Study of Ibrutinib in Pediatric and Young Adult Participants With Relapsed or Refractory Mature B-cell non-Hodgkin Lymphoma Seguridad y eficacia de ibrutinib en pacientes pediátricos y adultos jóvenes con Linfoma No Hodgkin
Part 1: Confirm that the pharmacokinetics in pediatric subjects is consistent with that in adults Part 2: Assess efficacy (EFS) of ibrutinib in combination with RICE or RVICI background therapy com...
Country
None
organs
None
Specialty
None
unknown
More information
Woman and Man Max 99 years
Ortho-McNeil Janssen Scientific Affairs, LLC
Update Il y a 5 ans
A Randomized, Double-blind, Parallel-group, Multicenter Study to Evaluate the Retention Rate, Efficacy, Safety, and Tolerability of Carisbamate, Topiramate and Levetiracetam as Adjunctive Therapy in Subjects with Partial Onset Seizures Estudio aleatorizado, doble ciego, de grupos paralelos, multicéntrico para evaluar el índice de retención, eficacia, seguridad y tolerabilidad de Carisbamato, Topiramato y Levetiracetam como terapia adyuvante en pacientes con crisis epilépticas parciales
The primary objective of this study is to demonstrate the long-term retention rate of CRS versus TPM and LEV when given adjunctively to subjects with partial onset seizures over a 6-month period.
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Janssen-Cilag EMEA Medical Affairs
Update Il y a 5 ans
A Phase II, Multicentre, Randomised, Open-Label, Parallel Group Study to Evaluate the Safety and Efficacy of Velcade® added to Thalidomide-Dexamethasone Standard Treatment in Subjects with Multiple Myeloma who are Refractory to or Have Relapsed after Primary Therapy for Multiple Myeloma
to assess the safety and efficacy of adding Velcade® to thalidomide and dexamethasone (Thal-Dex) standard treatment in subjects with multiple myeloma who are refractory to or have relapsed after thei...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Janssen Sciences Ireland UC
Update Il y a 5 ans
A Study to Research what the body does with the study drug after treatment with Simeprevir, Sofosbuvir and Ledipasvir in patients with Chronic Hepatitis C Virus Genotype 1 Infection who have not yet started anti-viral treatment
- To evaluate the effect of multiple-dose LDV 90 mg qd given in combination with SOF 400 mg qd on the steady-state PK of SMV 150 mg qd in chronic HCV genotype 1 infected subjects. - To evaluate the e...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man
Between 18 years
and 99 years
Janssen
Update Il y a 5 ans
Étude 54179060CLL3011-GLOW : étude de phase 3 randomisée comparant l’efficacité et la tolérance de l’ibrutinib en association avec du venetoclax par rapport au chlorambucil en association avec de l’obinutuzumab comme traitement de première ligne chez des patients ayant une leucémie lymphoïde chronique ou un lymphome à petits lymphocytes. [essai clos aux inclusions]
La leucémie lymphoïde chronique et le lymphome à petits lymphocytes sont des maladies cancéreuses du sang qui se distinguent par une multiplication incontrôlée de certaines cellules du système immunit...
Country
France
organs
Leucémies chroniques
,
Lymphomes non hodgkinien
Specialty
Thérapies Ciblées
,
Immunothérapie - Vaccinothérapie
,
Chimiothérapie
Essai clos aux inclusions
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