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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche par promoteur : AstraZeneca AB
Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
FAST – A randomised, open-label, parallel, multicentre Phase IIIb Study to evaluate the Efficacy and Safety of Quetiapine IR titrared over 4 Days in Patients with Acute Psychosis (Rapid versus Conventional Titration)
The main objective is to compare the efficacy of quetiapine IR in patients with acute schizophrenia, schizoaffective disorder, psychosis NOS or bipolar mania with psychotic symptoms, following rapid t...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A 6 Week Double-Blind, Placebo-controlled, Randomised, Parallel Group Phase IIa Study to Assess the Tolerability/Safety and Efficacy of AZD1236 as an Oral Tablet in Patients with Moderate to Severe COPD
To investigate the tolerability and safety of AZD1236, as an oral tablet, in COPD patients by assessment of: incidence and nature of adverse events vital signs and laboratory safety assessments
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A single-dose study to investigate the effects of 3 different doses of inhaled AZD2115 in COPD patients
To investigate the local bronchodilatory effects of 3 different doses of AZD2115 compared with placebo, with respect to peak and trough forced expiratory volume in the first second (FEV1), in patients...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
This is a randomized, placebo-controlled, double−blind study meaning neither the patient nor the study doctor will know which medication is being given. The study is randomized, meaning that participants will be randomly assigned to 1 of 3 treatment groups. To evaluate the efficacy, how the drug is absorbed in the blood stream and how safe is the study drug called AZD8871 when this is administered once daily during two weeks in patients with moderate to severe COPD
To evaluate the efficacy of inhaled AZD8871 in patients with moderate to severe COPD patients.
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medully Thyroid Cancer
To assess the objective response rates (ORR) for 150 mg and 300 mg/day of vandetanib in patients with advanced & progressive MTC. ORR = % of patients with a best response of complete or partial respon...
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
Ensayo fase I/II, abierto, multicéntrico, de AZD2281 oral en combinación con Cisplatino, para valorar la seguridad y tolerabilidad en pacientes con tumores sólidos avanzados, y para valorar la eficacia como terapia neoadyuvante en pacientes con cáncer de mama triple negativo A Phase I/II, Open Label, Multi-centre Study of AZD2281 Administered Orally in Combination with Cisplatin, to Assess the Safety and Tolerability in Patients with Advanced Solid Tumours, and to Assess Efficacy in the Neoadjuvant Setting for Patients with Triple Negative Breast Cancer
Primary objective: · Part A/Phase I: The primary objective is to determine the safety and tolerability of twice daily oral doses of AZD2281 when administered in combination with cisplatin to patients...
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A Phase II, Open, Randomised Study to Assess the Efficacy and Safety of AZD6244 vs. capecitabine (Xeloda) in Patients with Advanced or Metastatic Pancreatic Cancer, who have Failed First Line gemcitabine Therapy (Gemzar)
The primary objective of this study is to assess the efficacy of AZD6244 versus capecitabine in the treatment of advanced or metastatic pancreatic cancer by assessment of time to death (TTD).
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A comparison of Symbicort® Maintenance and Reliever Therapy (Symbicort Turbuhaler® 160/4.5 mg, one inhalation bid plus as-needed) and Symbicort Turbuhaler 160/4.5 mg, one inhalation bid plus terbutaline Turbuhaler 0.4 mg/inhalation as needed, for treatment of asthma – a 12-month, randomized, double-blind, parallel group, active-controlled, multinational phase III study in asthmatic patients aged 16 years and above
The primary objective of this study is to compare the efficacy of Symbicort® Maintenance and Reliever Therapy (SMART) (Symbicort Turbuhaler® 160/4.5μg, one inhalation bid plus as needed) with Symbicor...
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A double-blind, placebo controlled, randomized, two centre phase IIa pharmacodynamic cross-over study to assess the effect of AZD3355, 65 mg bid, on transient lower esophageal sphincter relaxations (TLESRs) in GERD patients with incomplete response to PPI
The primary objective of this study is to assess the effect of repeated oral administration of AZD3355, 65 mg bid, measured as reduction in the number of transient lower esophageal sphincter relaxatio...
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 5 ans
A phase IIa, double-blind, randomized, 2-way cross-over study to evaluate the effect of a single dose of AZD1386 95 mg compared to placebo in a multimodal experimental pain model on esophageal sensitivity in GERD patients with a partial response to PPI treatment
The primary objective of the study is to compare a single dose of AZD1386 to placebo on esophageal sensitivity to thermal stimuli 1.5 hours post dose in GERD patients who are partial responders to PPI...
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