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Kusajili – Centralise les essais cliniques mondiaux
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de votre recherche par promoteur : Merck Sharp & Dohme Corp
Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 5 ans
MK-3682B (MK-5172 + MK-3682 + MK-8408 Fixed Dose Combination (FDC)) in HCV GT1 or GT3 DAA Failures
(1)To evaluate the efficacy of the combination regimen of MK-5172, MK-3682 and MK-8408 with or without ribavirin as assessed by the proportion of subjects in each arm achieving SVR12 (Sustained Virolo...
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unknown
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 5 ans
A clinical research study of 28 weeks to test the safety/tolerability and effectiveness of an investigational study medication (subcutaneous SCH 900222/MK-3222) in improving the signs and symptoms of moderate-to-severe chronic plaque psoriasis, and to compare it to an approved medication for the treatment of psoriasis called etanercept. 28 hetes, 3. fázisú, randomizált, aktív komparátor és placebo kontrollos, párhuzamos elrendezésű vizsgálat a subcutan alkalmazású SCH 900222/MK-3222 hatásosságának és biztonságosságának/tolerálhatóságának a felmérésére, amelyet opcionális, a hosszú távú biztonságosságot érintő, kiterjesztett vizsgálat követ, középsúlyos-súlyos, krónikus, plakk típusú pikkelysömörben szenvedő betegeknél
Primary Efficacy Objective: To assess the efficacy of SCH 900222/MK-3222, hereafter referred to as MK-3222, compared to placebo in the treatment of moderate-to-severe chronic plaque psoriasis as measu...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., U.S.A
MAJ Il y a 5 ans
A Phase II Multicenter, Randomized, Double-Blind, Two-Stage Clinical Trial to Evaluate the Efficacy and Safety of MK-0594 in Patients with Alcohol Dependence
Evaluate efficacy of MK-0594 in maintaining absence of heavy alcohol drinking over Weeks 3-12 of a 12-week treatment period
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Essai clos aux inclusions
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Femme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 5 ans
A 2nd Open-Label Extension for 5 Years to: The Placebo-Controlled 1st Extension to a Randomized, Placebo-Controlled Clinical Trial to Assess the Safety and Efficacy of Odanacatib (MK-0822) to Reduce the Risk of Fracture in Osteoporotic Postmenopausal Women Treated With Vitamin D and Calcium
Objectives 1st extension: 1. To assess the effect of treatment up to 5 years with odanacatib on the risk of morphometrically assessed vertebral fractures compared to placebo. 2. To assess safet...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 5 ans
Study of safety and efficacy of different doses of the study drug, MK-0854/Losartan Potassium, in pediatric patients with high blood pressure assigned to different groups randomly. Treatment is known to doctor and patient
(1) To define a dose-response relationship for losartan in hypertensive children aged 6 months to 6 years, after a 21-day open-label treatment period (response assessed by change from baseline in mean...
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Essai clos aux inclusions
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Femme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 5 ans
Pembrolizumab in Subjects with Advanced Recurrent Ovarian Cancer
(1) To evaluate clinical anti-tumor activity of pembrolizumab monotherapy based on overall response rate (ORR) as assessed by CIV per RECIST 1.1 in Cohort A-All Comer group (2) To evaluate clinical...
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unknown
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Femme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 5 ans
A 24-Month Extension to: A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Efficacy of MK-0822 (Cathepsin-K Inhibitor) in the Treatment of Postmenopausal Women with Osteoporosis
For Base Study: To assess the effect of L-001037536 3 mg weekly, 10 mg weekly, 25 mg weekly, and 50 mg weekly on lumbar spine BMD compared to placebo over 12 months. For 24 Months Extension: To ...
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 5 ans
A Study of the Efficacy and Safety of MK-4618 in Patients with Overactive Bladder (OAB)
1. To assess the long-term safety and tolerability of treatment with MK-4618 compared to tolterodine ER. 2. To assess the long-term safety profile of MK-4618 dosed concomitantly with tolterodine ER...
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 5 ans
An Efficacy and Safety Trial of MK-8931 in Mild to Moderate AD (EPOCH)
Part I (main cohort) - Primary Trial Objectives: 1. To assess the efficacy of two doses of MK-8931 on cognition in subjects with mild to moderate AD. 2. To assess the efficacy of two doses of MK-893...
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Femme et Homme Max 99 ans
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
MAJ Il y a 5 ans
STUDY TO ASSESS CARDIOVASCULAR OUTCOMES FOLLOWING TREATMENT WITH ERTUGLIFLOZIN IN SUBJECTS WITH TYPE 2 DIABETES MELLITUS AND ESTABLISHED VASCULAR DISEASE ESTUDIO PARA EVALUAR LOS SUCESOS CARDIOVASCULARES TRAS EL TRATAMIENTO CON ERTUGLIFLOZINA EN PACIENTES CON DIABETES MELLITUS TIPO 2 Y ENFERMEDAD CARDIOVASCULAR ESTABILIZADA
Objective: To demonstrate the non inferiority of ertugliflozin compared with a non ertugliflozin comparator group on the time to first occurrence of any of the components of the composite endpoint of ...
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