A clinical trial to assess the long term safety of radium-223 dichloride To define the long-term safety profile of radium-223 dichloride (for up to 7 years after the last dose of radium-223 dichloride); to assess the incidence of leukemia, myelodysplastic syndrome, aplast...

• Country None
• organs None
• Specialty None

To determine oral bioavailability of the oral liquid formulation and potential food effects The primary objective of the study is to determine oral bioavailability of the liquid formulation intended for paediatric use and potential food effects in healthy adults.

• Country None
• organs None
• Specialty None

Effect of exercise alone or in combination with testosterone replacement on muscle strength and quality of life in older men with low testosterone concentrations: a randomized double-blind, placebo controlled study Additional effect of TRT in hypogonadal men on dynamic maximum strength (one repetition maximum, 1-RM) of upper and lower extremity

• Country None
• organs None
• Specialty None

A study to investigate the safety and tolerability of a 14 day oral treatment with different doses of BAY 1142524 in comparison to placebo in patients with left-ventricular dysfunction after myocardial infarction The primary objective of this pilot study is to investigate the safety and tolerability after multiple oral doses of BAY 1142524 administered BID (using 3 dose groups) or OD (using a 4th dose group) a...

• Country None
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• Specialty None

Efficacy and safety of a progestin and an aromatase inhibitor combined in a intravaginal ring in symptomatic endometriosis To assess the dose-response relationship and demonstrate efficacy of BAY 98-7196 vs. placebo in women with symptomatic endometriosis.

• Country None
• organs None
• Specialty None

Bayer 309544 : Essai de phase 2, randomisé évaluant l’efficacité et la tolérance de 4 schémas de traitement par épothilone, chez des patientes ayant un cancer du sein métastatique. [Informations issues du site clinicaltrials.gov et traduites par l'INCa] [essai clos aux inclusions] Prospective, Multicenter, Randomized, Independent-Group, Open-Label Phase II Study to Investigate the Efficacy, Safety and Tolerability of 4 Regimen With 3 Doses of ZK 219477 (16 and 12 mg/m<sup>2</su...

• Country France
• organs Sein
• Specialty Chimiothérapie

Radium-223 Chloride in the treatment patients diagnosed with prostate cancer that has spread to the bone Cloruro de radio-223 en el tratamiento de pacientes con diagnóstico de cáncer de próstata que se ha extendido a los huesos Provide radium-223 chloride to patients diagnosed with CRPC/HRPC with bone metastasis To assess acute and long-term safety of radium-223 chloride Administrar cloruro de radio-223 a pacientes a...

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• Specialty None

Study and implementation of urogenital schistosomiasis elimination in Zanzibar (Unguja and Pemba islands) Background and study aims Schistosomiasis is an infection caused by parasites that live in freshwater snails. It continues to be a major public health problem in many developing countries. However, i...

• Country None
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• Specialty None

PANACHE - A phase II trial to study neladenoson bialanate over 20 weeks in patients with chronic heart failure with preserved ejection fraction Find the optimal dose of neladenoson bialanate for the Phase III trial by detecting and characterizing a significant dose-response relationship in the primary efficacy endpoint, absolute change from b...

• Country None
• organs None
• Specialty None

Long-term pre-dialysis extension of darbepoetin treatment versus BAY 85-3934 in Europe and Asia Pacific 1) To evaluate efficacy of treatment with BAY 85-3934 compared with darbepoetin alfa as measured by change from baseline to post-baseline time points in haemoglobin (Hb) levels. 2) To evaluate safet...

• Country None
• organs None
• Specialty None