A study to evaluate the safety and effect of the 2 experimental drugs ABT-493/ABT-530 in people with HCV. "Experimental" means that they have not been approved by any regulatory agency for sale to the public The primary objectives of this study are to assess the efficacy (SVR12) HCV RNA < lower limit of quantification (LLOQ) 12 weeks following 12 weeks of treatment of the ABT-493/ABT-530 combination regim...

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Phase 2 Study, Multicenter, Open-Label Extension (OLE) Study in Rheumatoid Arthritis Subjects Who Have Completed a Preceding Phase 2 Randomized Controlled Trial (RCT) with ABT-494 To evaluate the long-term safety, tolerability, and efficacy of ABT-494 in RA subjects who have completed Study M13-550 or Study M13-537 Phase 2 RCT with ABT-494.

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A Multicenter, Randomized, Double-Blind, Study Comparing the Efficacy and Safety of Continuing Versus Withdrawing Adalimumab Therapy in Maintaining Remission in Subjects with Non Radiographic Axial Spondyloarthritis Multicentrická, randomizovaná, dvojitě zaslepená studie porovnávající účinnost a bezpečnost pokračující terapie adalimumabem oproti ukončení léčby adalimumabem u pacientů s axiální spondylartritidou bez radiologického průkazu ve stádiu remise The objective of this study is to evaluate the efficacy and safety of continuing versus withdrawing therapy with adalimumab 40 mg given every other week (eow) subcutaneously (SC) in maintaining remiss...

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A study to evaluate the safety and efficacy of ombitasvir/ABT-450/ritonavir with sofosbuvir with or without ribavirin in adults with Chronic Hepatitis C Virus infection Percentage of subjects with sustained virologic response 12 weeks post-treatment.

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A trial studying the efficacy & safety of ABT-126 in subjects with mild to moderate Alzheimer's Disease Evaluate the dose-response relationship with respect to the efficacy of symptomatic treatment and safety of three doses of ABT-126 in subjects with mild to moderate AD. The primary efficacy measure i...

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Randomized, Open-Label, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Co-Administration of ABT-493 and ABT-530 with and without RBV in Subjects With Chronic Hepatitis C Virus (HCV) Genotypes 2, 3, 4, 5 or 6 Infection To assess the efficacy and safety of ABT-493 and ABR-530 (or ABT-493/ABT-530) with or without RBV in subjects with chronic HCV genotype 2, 3, 4, 5 or 6 infection. In Part 4, the primary objectives inc...

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A Multicenter Open-Label, Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir in Renally-Impaired Adults with Chronic Hepatitis C Virus Genotype 1 – 6 Infection Πολυκεντρική, Ανοικτή Μελέτη για την Αξιολόγηση της Αποτελεσματικότητας και της Ασφάλειας του Glecaprevir/Pibrentasvir σε Ενήλικες με Νεφρική Δυσλειτουργία με Χρόνια Λοίμωξη με Ιό Ηπατίτιδας C Γονοτύπου 1 – 6 To assess the efficacy (by evaluating the percentage of subjects achieving SVR12) and safety of glecaprevir/pibrentasvir (GLE/PIB) in adults with chronic hepatitis C virus (HCV) genotype (GT) 1 – 6 in...

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Étude M14-237 : étude de phase 1-1b, en escalade de dose, évaluant la tolérance et l’efficacité d’ un anticorps ciblant la protéine MET, couplé à un agent cytotoxique, chez des patients ayant une tumeur solide avancée, présentant une surexpression de MET. M14-237 Etude de phase I/Ib d'escalade de dose, multicentrique, en ouvert, évaluant l'ABBV-399, un conjugué anticorps-médicament, chez des patients atteints de tumeurs solides avancées.

• Pays France
• Organes Tumeurs solides
• Spécialités Thérapies Ciblées

Double-Blind, Randomized, Placebo Controlled Multicenter Study to Assess the Safety and Efficacy of Adalimumab Used in Conjunction with Surgery in Subjects with Moderate to Severe Hidradenitis Suppurativa Assess the safety and efficacy of adalimumab prior to surgery in subjects with moderate to severe Hidradenitis Suppurativa (HS) who are surgical candidates.

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A Multicenter Open-label Study of the Human Anti-TNF Monoclonal Antibody Adalimumab to Investigate Efficacy, Safety and Pharmacokinetics after Dose Escalation in Japanese Subjects with Crohn's Disease To investigate efficacy, safety and pharmacokinetics after dose escalation for the subjects who lost response to adalimumab in Japanese patients with Crohn's disease.

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