An Open Label Study Evaluating the Safety and Efficacy of Long-Term Dosing of Romiplostim in Thrombocytopenic Pediatric Subjects with immune (Idiopathic) Thrombocytopenia Purpura (ITP).------------------------------------------------ Estudio Abierto para Evaluar la Seguridad y Eficacia del Tratamiento a Largo Plazo con Romiplostim en Sujetos Pediátricos Trombocitopénicos con Púrpura Trombocitopénica Inmune (Idiopática) (PTI) The primary objective of this study is to evaluate the safety of romiplostim as a long-term treatment in pediatric thrombocytopenic subjects with immune (idiopathic) thrombocytopenic purpura (ITP).

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A Phase 1b/2 Trial of AMG 655 in Combination with Panitumumab in Subjects with Metastatic Colorectal Cancer This study is divided into 2 parts: a phase 1b portion (part 1) and a phase 2 portion (part 2). Part 1: The primary objective of part 1 is to identify a tolerable dose of AMG 655 in combination with...

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A Study of the Effects of AMG 334 to Prevent Migraine Headaches To evaluate the effect of AMG 334 compared to placebo on the change from baseline in monthly migraine days, in subjects with episodic migraine

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A Randomized, Placebo Controlled Study Evaluating the Efficacy and Safety of AMG 531 Treatment of Thrombocytopenic Subjects with Immune (Idiopathic) Thrombocytopenic Purpura (ITP) Prior to Splenectomy To evaluate the efficacy of AMG 531 in the treatment of thrombocytopenia in subjects with ITP as measured by the platelet response

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A Study to Evaluate the Effect of Treatment with AMG 785 in Postmenopausal Women with Osteoporosis Previously Treated with BisphosphonateTherapy Evaluate the effect of treatment with AMG 785 for 12 months, compared with teriparatide (TPTD), on total hip bone mineral density (BMD), as assessed by dual energy X-ray absorptiometry (DXA), in post...

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A Study of the Effects of AMG 334 to Prevent Migraine Headaches To characterize the safety and tolerability of long-term administration of AMG 334

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This study is being done to learn more about long-term use of evolocumab, safety and tolerability, and whether its chronic administration is associated to any side effects - To describe the safety and tolerability of long-term administration of evolocumab.

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The trial is designed to determine the efficacy and safety of ABP 215 compared with Bevacizumab in subjects with advanced non-small cell lung cancer El ensayo se ha diseñado para determinar la eficacia y la seguridad de ABP 215 comparado con bevacizumab en sujetos con cáncer de pulmón no microcítico avanzado To compare the efficacy of ABP 215 with bevacizumab. Comparar la eficacia del ABP 2015 con la del bevacizumab.

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Study is to find out more about evolocumab in HIV-positive patient`s and with high cholesterol (hyperlipidemia and/or mixed dyslipidemia) To evaluate the effect of 24 weeks of subcutaneous (SC) evolocumab administered every month (QM) compared with placebo QM on percent change from baseline in low-density lipoprotein cholesterol (LDL-C)...

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This trial is designed to determine what effects the human body has on the investigational medicine, ABP 710, and what effects the body has on the investigational medicine after you have been given it, and if this is comparable to what is seen for the licensed medicine, infliximab, in patients with moderate or severe rheumatoid arthritis (RA). This study will assess if the investigational medicine is safe and effective in treating moderate or severe RA compared to the licensed medicine. Este ensayo ha sido diseñado para determinar los efectos del cuerpo humano sobre el fármaco experimental, ABP 710, así como los efecto del cuerpo sobre el fármaco en investigación después de haberlo administrado, y verificar si son comparables a los efectos observados con el fármaco aprobado, infliximab, en pacientes con artritis reumatoide (AR) de moderada a grave The primary objective for this study is to assess the efficacy of ABP 710 compared with US-licensed infliximab (infliximab). El objetivo principal de este estudio es evaluar la eficacia de ABP 7...

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