Tribendimidine for the treatment of liver fluke infection in Southeast Asia in Laos Background and study aims Opisthorchiasis and clonorchiasis are parasitic liver fluke infections that are of considerable public health significance in Southeast Asia. There is currently no vaccine a...

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The effect of graded exercise and counselling with usual care plus a booklet for patients with fatigue in primary care Not provided at time of registration

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Sulfadoxine-pyrimethamine combinations study Background and study aims Malaria is a serious tropical disease caused by a parasite that is spread by mosquitoes. Antimalarial medication is used to prevent and treat malaria. However, resis...

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A randomised trial comparing the clinical and cost effectiveness of usual, facility based care compared to an additional collaborative community care package for people and their families living with schizophrenia in India Background and study aims. Community based services for people with schizophrenia are largely lacking in low and middle income country (LAMIC) settings. The lack of accessible care leads to a very la...

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The efficacy of chloroquine in treatment of vivax malaria in southern Laos Not provided at time of registration

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A randomised controlled trial of brief cognitive therapy for social phobia (social anxiety disorder) Not provided at time of registration

• Pays United Kingdom
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Individual placement and support (IPS) to improve occupational outcomes for people with severe mental illness Not provided at time of registration

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Image guidance with image overlay for laparoscopic surgery Background and study aims During keyhole liver surgery (laparoscopic liver resection), some internal structures may be difficult to distinguish from one another or difficult to see as they are deep w...

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STEPped-CARE intervention for depression in primary care Background and study aims It is estimated that depressive disorders (illnesses involving low mood) will become the third most burdensome health problem in the low income countries after HIV/AIDS and c...

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Program for effective mental health interventions in under-resourced health systems Background and study aims Depression accounts for the highest burden of disease of any mental disorder. Most patients with depression seek healthcare through their GP surgeries. The WHO recommends the...

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