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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche par promoteur : AstraZeneca AB
Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A 4 week double-blind, placebo-controlled, randomized, parallel group phase IIa study to assess the efficacy and safety of AZD1981 in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD)
The primary objective is to evaluate the efficacy of AZD1981 as compared with placebo in patients with moderate to severe COPD.
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A randomised, double-blind, placebo-controlled study to evaluate the transthoracic Doppler echocardiography method as a non-invasive method for coronary function measurements; ability to detect short-term statin effects in patients with increased cardiovascular risk
· To evaluate the change after 1 month statin treatment in transthoracic Doppler echocardiography-coronary flow reserve (TTDE-CFR) peak velocity compared to baseline within the rosuvastatin 40 mg grou...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A double-blind, placebo controlled, randomised, parallel group phase IIa study to investigate the efficacy, tolerability, and safety of different dosing regimens of AZD8848 administered intranasally to seasonal allergic rhinitis patients out of pollen season in a nasal allergen challenge model
Primary Objective: To compare the efficacy of 60 μg AZD8848 once weekly with 20 μg AZD8848 three (3) times weekly and with placebo when administered intranasally to seasonal allergic rhinitis patients...
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Essai clos aux inclusions
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Femme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
An Open Label, Randomised, Parallel Group, Multicentre Study to Compare ZOLADEX™ 10.8 mg Given Every 12 Weeks with ZOLADEX 3.6 mg Given Every 4 Weeks in Pre-menopausal Women with Oestrogen Receptor Positive Advanced Breast Cancer
The primary objective of this study is to evaluate whether ZOLADEX 10.8 mg is non-inferior to ZOLADEX 3.6 mg in pre-menopausal women with oestrogen receptor (ER) positive advanced breast cancer (ABC) ...
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Essai clos aux inclusions
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Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A Phase III, Randomised, Placebo-controlled, Double-blind Study to Assess the Efficacy and Safety of Once-daily Orally Administered ZD4054 10 mg in Non-metastatic Hormone-resistant Prostate Cancer Patients
1. To determine the effect of ZD4054 on overall survival compared to placebo 2. To assess the effect of ZD4054 on progression free survival compared to placebo
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
Real World Treatment Study of AZD9291 for Advanced/Metastatic EGFR T790M Mutation (NSCLC) Estudio acerca del tratamiento en la práctica real con AZD9291 para la mutación T790M Avanzada/Metastática EGFR T790M , en cáncer de pulmón no microlítico (CPNM)
The primary objective of this study is to assess the efficacy and safety of single agent AZD9291 in a real world setting in adult patients with advanced or metastatic, epidermal growth factor receptor...
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A comparison of treatment with Saxagliptin and Dapagliflozin against Insulin Glargine in Type 2 Diabetes patients whose current treatment of Metformin with or without Sulfonylurea Therapy is not adequate
To examine whether the mean change from baseline in HbA1c with co-administered saxagliptin 5 mg and dapagliflozin 10 mg plus metformin with or without SU is non-inferior to titrated insulin glargine p...
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unknown
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A RANDOMIZED PHASE II TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF VANDETANIB (ZD6474, ZACTIMATM) VERSUS VINORELBINE IN PATIENTS WITH INOPERABLE OR RELAPSED MALIGNANT MESOTHELIOMA
To evaluate the efficacy of oral vandetanib 300 mg once daily compared with vinorelbine administrated intravenously weekly in patients with inoperable or relapsed malignant mesothelioma by estimating ...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB
MAJ Il y a 4 ans
A Phase IV Prospective, Double-blind, Double-dummy, Randomised, Crossover Study to Assess the Impact on Daily Cognitive Functioning of Quetiapine Fumarate Immediate Release (Seroquel IR®) Dosed twice Daily and Quetiapine Fumarate Extended Release (Seroquel XR®) Dosed once Daily in the Evening in Patients with Stable Schizophrenia
The primary objective of this study is to demonstrate that patients with stable schizophrenia show superior daytime cognitive performance when taking quetiapine XR once daily in the evening compared t...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
AstraZeneca AB, AstraZeneca Sverige
MAJ Il y a 4 ans
A randomised, double blind, double dummy, multicentre phase III study comparing the efficacy of budesonide/formoterol (Symbicort® forte Turbuhaler®) and oral prednisolone + formoterol (Oxis® Turbuhaler) during two weeks, in COPD patients with an acute exacerbation, followed by twelve weeks open follow up period with budesonide/formoterol (Symbicort forte Turbuhaler) - SPACE
To assess if a double standard dose of Symbicort forte Turbuhaler during two weeks is as effective as an oral course of prednisolone + Oxis Turbuhaler (during two weeks) for the treatment of an acute ...
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Essai clos aux inclusions
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