Metabolic Activation With Protein-rich Formula Diet Formerly, the investigators demonstrated in an uncontrolled proof-of principle study (NCT 01680926) that protein-rich meal replacement (PRMR) was successful in reducing daily insulin deman...

• Country None
• organs None
• Specialty None

Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the Knee The primary objective of this study is to evaluate the analgesic efficacy of 2 dose levels of V116517 versus placebo.

• Country None
• organs None
• Specialty None

Bulking Agents for the Treatment of Stress Urinary Incontinence in Females The primary purpose of this study is to demonstrate the safety and effectiveness of Bulkamid® in the treatment of stress urinary incontinence (SUI) due to intrinsic sphincter deficiency (I...

• Country Canada, France, United States
• organs None
• Specialty None

Study Protocol for CTS and Keyboard Controlled Randomized Trial The study hypothesis is that there is a relationship between the keyboard layout and carpal tunnel syndrome (CTS). Specifically, use of the standard QWERTY keyboard increases the risk of s...

• Country None
• organs None
• Specialty None

MiQuit Trial: Tailored Text Messages for Pregnant Women The overall aim of the study is to estimate the likely impact of the MiQuit text message based smoking cessation service for pregnant smokers and to establish robust estimates for the key ...

• Country None
• organs None
• Specialty None

Renal Impairment Study of Empagliflozin (BI10773) in Japanese Patients With Type 2 Diabetes The objective of this study is to assess the effect of the different degrees of renal impairment on the pharmacokinetics, pharmacodynamics and safety of BI10773 following oral administrati...

• Country None
• organs None
• Specialty None

Pentasa Once Daily in Ulcerative Colitis for Maintenance of Remission This is a multi-centre, randomised, controlled, investigator blinded study. The randomisation will be done centrally. The patients will be treated for 1 year, with clinical and laboratory ...

• Country None
• organs None
• Specialty None

Evaluation of the Physiopathological Phenomena and the Haemodynamic and Cerebral Metabolic Effects From Semi-seated Position to Lying Position in Patients With Brain Trauma Brain trauma is an important burden in traumatologic intensive care. In these patients the treatment is guided by a cluster of multimodal monitoring parameters. Despite this it is difficul...

• Country None
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• Specialty None

Local Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers The "dry eye syndrome" DES is a highly prevalent ocular disease, in particular in the elderly population. One mainstay of therapy for patients suffering from DES is the use of topically ad...

• Country None
• organs None
• Specialty None

A Multicenter, Randomized, Placebo-Controlled Phase 2 Study to Evaluate the Clinical Efficacy, Safety, and Tolerability of ARX-F01 Sublingual Sufentanil in Patients Undergoing Major Abdominal Surgery The purpose of this study is to evaluate dosages of ARX-F01 (opioid pain medication) versus a placebo (or sugar pill) for the treatment of post-operative pain in subjects following abdomin...

• Country None
• organs None
• Specialty None