A study to assess the safety and efficacy of ledipasvir/sofosbuvir in adults with chronic HCV infection - To determine the antiviral efficacy of ledipasvir/sofosbuvir (LDV/SOF) +/- ribavirin (RBV) in subjects with chronic HCV infection as measured by the proportion of subjects in each treatment group wi...

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A study with sofosbuvir and ribavirin for adolecents and children with chronic Hepatitis C infection The primary objective of the PK Lead-in Phase of this study is: *To evaluate the steady state pharmacokinetics (PK) and confirm the dose of sofosbuvir (SOF) in HCV-infected pediatric subjects The prim...

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An international study to assess the safety and efficacy of a combination of an approved drug combination in different type of patient, namely patients acutely infected with Hepatitis C virus who are also chronically infected with Human Immunodeficiency Virus (HIV)-1 The primary objective of this study is as follows: • To determine the antiviral efficacy of LDV/SOF FDC Tablet as measured by the proportion of subjects who attain SVR at 12 weeks after discontinua...

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An international study to assess the safety and efficacy of a combination of new investigational drugs in patients with chronic hepatitis C virus infection who have previously failed treatment in a clinical study run by Gilead. Estudio internacional para evaluar la seguridad y eficacia de una combinación de nuevos medicamentos en investigación en pacientes con infección crónica por virus de la hepatitis C cuyo tratamiento previo en un estudio patrocinado por Gilead haya fracasado The primary objectives of this study are: - To determine the efficacy of sofosbuvir/ledipasvir fixed-dose combination (SOF/LDV FDC) ± ribavirin (RBV) as measured by the proportion of subjects with sus...

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A Phase 2 clinical trial investigating the anti-virus effects, kinetics and safety of GS-5806 in adults with RSV (Respiratory Syncytial Virus) infection To evaluate the effect of presatovir on RSV viral load in autologous or allogeneic HCT recipients with an acute RSV LRTI

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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of 48 Weeks of GS-9190 in Combination with Peginterferon Alfa 2a (Pegasys®) and Ribavirin (Copegus®) in Previously Untreated Subjects with Genotype-1 Chronic Hepatitis C Virus (HCV) Infection To compare the antiviral efficacy (sustained virologic response; SVR) of 48 weeks of GS-9190 versus placebo when administered in combination with 48 weeks of peginterferon alfa 2a (PEG) and ribavirin...

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A study to investigate a new drug to treat Type 2 Diabetes The primary objective of this study is to: • Determine the effect of ranolazine monotherapy on HbA1c in subjects with T2DM who are inadequately controlled with diet and exercise alone and who are t...

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A trial looking at the treatment of SOF/GS-5816 in patients with hepatitis C infection - To evaluate the efficacy of treatment with SOF/GS-5816 for 12 weeks in subjects with chronic HCV infection as measured by the proportion of subjects with SVR12 - To evaluate the safety and tolera...

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A Phase 2 clinical trial investigating the anti-virus effects, kinetics and safety of GS-5806 in adults with RSV (Respiratory Syncytial Virus) infection To evaluate the effect of GS-5806 on RSV viral load in RSV-positive autologous or allogeneic HCT recipients with acute URTI symptoms

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A study comparing 3 different treatments and treatment durations for hepatitis C The primary objectives of this study are: - To determine the efficacy of sofosbuvir (SOF)+ Ribavirin (RBV) for 16 or 24 weeks as measured by the proportion of subjects with sustained viral response 12...

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