Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria The purpose of this study is to evaluate three dose levels of a combination of pyronaridine and artesunate for the treatment of uncomplicated falciparum malaria in children.

• Country Gabon
• organs None
• Specialty None

A Comparative Safety and Activity Study With Ferroquine Associated With Artesunate Versus Amodiaquine Associated With Artesunate in African Adult Patients With Uncomplicated Malaria The primary objective is to assess the safety of different doses of ferroquine with artesunate (AS) in adult African patients with uncomplicated malaria. The secondary objectives are to a...

• Country Gabon, Kenya
• organs None
• Specialty None

Treatment of Non-falciparum Malaria Patients with non-falciparum infection will be given artemether-lumefantrine for three days and will be followed up for 28 days. Besides efficacy and safety evaluations a substudy on immun...

• Country Gabon
• organs None
• Specialty None

Treatment of Malaria With Quinine Plus Sulfadoxine-Pyrimethamine Quinine remains the treatment of choice of hospitalised malaria cases. The long treatment duration of 7 days, and adverse reactions often hamper its adequate use. Reducing the treatment du...

• Country Gabon
• organs None
• Specialty None

Treatment of Fever Due to Malaria With Ibuprofen Drugs to treat fever are widely used in children with fever. But there is a controversy about the benefit of reducing fever in children with malaria. Ibuprofen is often used to treat malar...

• Country Gabon
• organs None
• Specialty None

Phase II Artesunate Study in Severe Malaria The primary objective of the study is to evaluate the effectiveness of 2 intravenous artesunate dosing regimens (2.4 mg/kg initially and at 12, 24, 48, and 72 hours or 4.0 mg/kg initially ...

• Country Gabon, Malawi
• organs None
• Specialty None