An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy The purpose of this study is to evaluate clinical effectiveness and safety of golimumab with methotrexate (MTX) in the treatment of rheumatoid arthritis (RA) when compared to MTX alone.

• Pays Argentina, Australia, Colombia, Hungary, Korea, Republic of, Lithuania, Malaysia, Mexico, New Zealand, Poland, Russian Federation, Ukraine, United States
• Organes Aucun
• Spécialités Aucune

Delay Future End Stage Nephropathy due to Diabetes

• Pays New Zealand
• Organes Aucun
• Spécialités Aucune

Pharmacokinetics, Safety, and Tolerability Study of the Pen and PFS of SB5 in Healthy Subjects The purpose of this study is to compare the pharmacokinetics, safety, and tolerability of the pre-filled pen and pre-filled syringe of SB5 in healthy subjects.

• Pays Belgium, New Zealand
• Organes Aucun
• Spécialités Aucune

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of AMG 811 in Subjects With Psoriasis The purpose of this study is to assess the safety, tolerability, immunogenicity, and clinical effects of AMG 811 following single subcutaneous dose administration in subjects with moderate...

• Pays Australia, New Zealand
• Organes Aucun
• Spécialités Aucune

Nicotine Pharmacokinetic and Pharmacodynamics Profile, Safety and Tolerability of P3L The purpose of this study is to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD, i.e., subjective effects) profiles, and the safety and tolerability of the nicotine-containing ...

• Pays New Zealand
• Organes Aucun
• Spécialités Aucune

Collection of Blood Samples From SMART Study Participants for Future Genetic Studies The purpose of this study is to collect blood samples from SMART study participants to use in future genetic studies.

• Pays American Samoa, Australia, Belgium, Canada, Chile, Denmark, Finland, Gambia, Germany, Japan, Morocco, New Zealand, Poland, Portugal, United States, Uruguay
• Organes Aucun
• Spécialités Aucune

A Study of the Efficacy, Safety and Tolerability Profile of CSL Limited's Influenza Virus Vaccine (CSL's IVV) Administered Intramuscularly in Healthy Adults This study will assess the Efficacy, Safety and Tolerability profile of CSL's Influenza Vaccine administered intramuscularly against laboratory-confirmed influenza illness in a population ...

• Pays Australia, New Zealand
• Organes Aucun
• Spécialités Aucune

Dose Ranging Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate The purpose of this clinical trial is to assess the safety, efficacy, tolerability, immunogenicity and pharmacokinetics of 3 dose levels of ART621 in the treatment of rheumatoid arthritis.

• Pays Argentina, Australia, Czech Republic, India, Malaysia, New Zealand, Poland, United States
• Organes Aucun
• Spécialités Aucune

Vernakalant (Oral) Prevention of Atrial Fibrillation Recurrence Post-Conversion Study To evaluate the safety, tolerability and efficacy of 3 doses of vernakalant (oral) (150 mg, 300 mg and 500 mg b.i.d.) administered for up to 90 days in subjects with sustained symptomatic ...

• Pays Germany, Hungary, Lithuania, Netherlands, New Zealand, Poland, Portugal, Romania, Russian Federation, Serbia, Singapore, Slovakia, South Africa, Spain, Sweden, Switzerland, Ukraine, Australia, Belgium, Bulgaria, Croatia, Czech Republic, Denmark, Estonia
• Organes Aucun
• Spécialités Aucune

Delanzomib (CEP-18770) in Combination With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma The primary objective of the study is to determine the maximum tolerated dose (MTD) of CEP-18770 in combination with lenalidomide and dexamethasone in patients with relapsed or refractory ...

• Pays New Zealand, United States
• Organes Aucun
• Spécialités Aucune