Glucarpidase Effect on Severe Delayed HDM-clearance in Children Treated With High-dose Mtx in ALL

Update Il y a 4 ans
Reference: NCT01305655

Woman and Man

Extract

Early intervention in children and adolescents who experience delayed MTX-clearance and renal dysfunction in ALL treatments with the enzyme Glucarpidase which rapidly hydrolyses MTX to non-toxic metabolites to avoid life threatening complications.


Inclusion criteria

  • Acute lymphoblastic leukemia [ALL]


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