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A Randomized, Open-Label Study to Compare the Safety and Efficacy of Conversion From a Calcineurin Inhibitor to Sirolimus Versus Continued Use of a Calcineurin Inhibitor in Cardiac Transplant Recipien...

Update Il y a 4 ans
Reference: EUCTR2006-002420-41

A Randomized, Open-Label Study to Compare the Safety and Efficacy of Conversion From a Calcineurin Inhibitor to Sirolimus Versus Continued Use of a Calcineurin Inhibitor in Cardiac Transplant Recipients With Mild to Moderate Renal Insufficiency

Woman and Man

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Extract

To demonstrate the superiority of converting from CNI therapy to sirolimus therapy to continuing CNI therapy with respect to renal function in cardiac transplant recipients with mild to moderate renal dysfunction.

Inclusion criteria

  • Cardiac transplant recipients with mild to moderate renal insufficiency

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