Phase III Randomized Controlled Trial of Pembrolizumab with or without Chemo vs Chemo in Advanced Urothelial Carcinoma

Update Il y a 4 ans
Reference: EUCTR2015-005731-41

Woman and Man

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Extract

To compare Progression Free Survival (PFS) using RECIST 1.1 as assessed by (Blinded Independent Central Review) BICR and Overall Survival (OS) in PD-L1 positive subjects and all subjects with advanced or metastatic urothelial carcinoma treated with: (a) Pembrolizumab + chemotherapy versus chemotherapy (b) Pembrolizumab versus chemotherapy


Inclusion criteria

  • Advanced or Metastatic Urothelial Carcinoma