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A Worldwide, Double-Blind, Randomized, Placebo-Controlled Study of MK-0524A 2g Coadministered with Intensive LDL-C Lowering Therapy Compared to Intensive LDL-C Lowering Therapy Alone on Carotid Artery...

Update Il y a 4 ans
Reference: EUCTR2006-001913-13

A Worldwide, Double-Blind, Randomized, Placebo-Controlled Study of MK-0524A 2g Coadministered with Intensive LDL-C Lowering Therapy Compared to Intensive LDL-C Lowering Therapy Alone on Carotid Artery Intima Medial Thickening (cIMT) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

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Extract

In patients with heterozygous familial hypercholesterolemia (HeFH): (1) To demonstrate the effects of MK-0524A coadministered with intensive low-density lipoprotein cholesterol (LDL-C) lowering therapy compared to intensive LDL C lowering therapy alone on atherosclerosis progression as measured with non-invasive B-mode ultrasound carotid artery intima medial thickening (cIMT) measurements.

Inclusion criteria

  • heterozygous familial hypercholesterolemia (HeFH)

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