Chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastases The CHARISMA randomized multicenter clinical trial Chemotherapie gevol...

Update Il y a 4 ans
Reference: EUCTR2013-004952-39

Chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastases The CHARISMA randomized multicenter clinical trial Chemotherapie gevolgd door chirurgie versus chirurgie alleen in hoog-risico patienten met resectabele colorectale levermetastasen De CHARISMA gerandomiseerde multicenter trial

Woman and Man

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Extract

The primary objective of the study is to compare the efficacy, as assessed by overall survival (OS), of surgery and neo-adjuvant chemotherapy to surgery alone in patients with liver metastases of colorectal cancer and a high clinical risk score. Doel van de studie is om de effectiviteit van chirurgie met neo-adjuvante chemotherapie te vergelijken met chirurgie alleen in patienten met colorectale levermetastasen en een hoge risico score.


Inclusion criteria

  • Colorectal liver metastases,Colorectale levermetastasen

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