Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)

Update Il y a 4 ans
Reference: NCT01406977

Woman and Man

  • | Country :
  • Germany
  • | organs :
  • -
  • | Specialty :
  • -

Extract

The purpose of the study is to determine tolerability, PK/PD and preliminary efficacy of BPS804 in adult patients with HPP treated with multiple escalating doses of BPS804. This study will allow a comparison of several doses of the study drug within the first two weeks after administration and after a longer assessment period for the highest dose level to enable selection of dose ranges to be tested in subsequent studies in the HPP indication.


Inclusion criteria

  • Hypophosphatasia

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