High-dose Ribavirin in Treatment of Chronic Hepatitis C Genotype 1 or 4

Update Il y a 5 ans
Reference: NCT00662220

Woman and Man

Extract

Optimal ribavirin dosages are essential in achieving SVR (sustained virological response). Several studies have shown higher SVR rates in patients receiving higher doses of ribavirin. Therefore we propose a randomized controlled open label multicenter trial to investigate wether high (25-29mg/kg) dose ribavirin can improve outcome in patients in infected with hepatitis C virus genotype 1 or 4 compared to standard dose (12-15mg/kg).


Inclusion criteria

  • Chronic hepatitis C