A Phase 2a Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients with Knee Osteoarthritis

Update Il y a 4 ans
Reference: EUCTR2013-003467-60

Woman and Man

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Extract

To assess the effect of ABT-981 on OA knee pain using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at Week 16 and synovitis/effusion volume of the index knee using quantitative measures and semi-quantitative MRI scoring at Week 26 in patients with knee osteoarthritis.


Inclusion criteria

  • Adult male and female patients with mild to moderate, symptomatic, radiographic and inflammatory osteoarthritis of the knee