Testing the responsiveness of patients admitted to intensive care units to treatment with anti-platelet drugs (acetylsalicylic acid, clopidogrel, prasugrel, ticagrelor) To examine whether high "on treatment" platelet reactivity (HTPR) in acetylsalicylic-acid treated patients can be overcome by using intravenous ASA or crushed chewable ASA tablets or dose increase; To...

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Safety and efficacy study of bosentan in progressive pulmonary sarcoidosis • To demonstrate treatment efficacy of bosentan as add-on therapy in progressive pulmonary sarcoidosis in comparison to placebo, as measured by a composite clinical score based on pulmonary function t...

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Latanoprost preserved versus unpreserved: effect on tear film thickness To study the effect of randomizing glaucoma or ocular hypertension patients who are on preserved prostaglandin formulations to either preservative free latanoprost or preserved latanoprost on tear fil...

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Effects of simvastatin in patients after cardioversion (SIPAC) of non valvular atrial fibrillation To investigate the effects of statin treatment on (hs)-CRP-levels

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Acetylic salicylic acid for the treatment of Chronic Obstructive Pulmonary Disease (COPD). A randomized, double-blind, placebo-controlled trial To evaluate the effect of ASA as add-on therapy in COPD patients in comparison to placebo in spirometric and clinical regard, and to evaluate safety of this therapy.

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