A Study in Older Patients Undergoing Elective Total Hip Replacement The primary objective of this study is to test the hypothesis that appendicular lean body mass (aLBM) will increase after 12 weeks of LY2495655 treatment versus placebo in older patients undergoing el...

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An exploratory Phase 2 study of Pemetrexed and Cisplatin as Preoperative chemotherapy in the treatment of Stage IIIAN2 nonsquamous non-Small cell lung cancer Assess the antitumor activity of pemetrexed in combination with cisplatin, as measured by Overall Response Rate after preoperative chemotherapy, in patients with stage IIIAN2 nonsquamous NSCLC

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Use of Duloxetine or Pregabalin in Monotherapy versus Combination Therapy of Both Drugs in Patients with Painful Diabetic Neuropathy “The COMBO - DN (COmbination vs Monotherapy of pregaBalin and dulOxetine in Diabetic Neuropathy) Study” To evaluate whether treatment at standard doses with duloxetine (60 mg/day) in combination with pregabalin (300 mg/day) is superior to a maximal dose of duloxetine (120 mg/day) or pregabalin (600 mg/d...

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Progress of Mild Alzheimer’s Disease in Patients on Solanezumab versus Placebo To test the hypothesis that solanezumabwill slow the cognitive and functional decline of AD as compared with placebo in patients with mild AD.

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Effectiveness of Prasugrel versus Clopidogrel in Subjects with High Platelet Reactivity on Clopidogrel Following Elective Percutaneous Coronary Intervention with Implantation of Drug-Eluting Stent To estimate the relative risk of the composite endpoint of Clinical Events Committee (CEC) adjudicated cardiovascular (CV) death or myocardial infarction (MI) through 6 months of maintenance treatment...

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Clinical Trial Testing the Safety of Four Ramucirumab Doses Given as Second Line Treatment to Patients with Stomach Cancer Evaluate ramucirumab PK following various dose regimens. Assess the safety for each dose group of ramucirumab in patients with advanced gastric cancer, whose disease has progressed during or following...

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Duloxetine 60 to 120 mg Once Daily Compared with Placebo in the Prevention of Relapse in Generalized Anxiety Disorder to assess the long-term maintenance of efficacy of duloxetine 60 to 120 mg once daily (QD) compared with placebo by a comparison of the time to relapse among patients with Diagnostic and Statistical M...

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Efficacy of Once-Weekly Exenatide versus Once or Twice Daily Insulin Detemir in Patients with Type 2 Diabetes Treated with Metformin Alone or in Combination with Sulphonylurea The primary objective of this study is to test the hypothesis that exenatide QW given once weekly for 26 weeks is superior to a titration of insulin detemir, given once or twice daily (titrated to rea...

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A study in Lupus To evaluate the effect of baricitinib 4-mg once daily (QD) or 2-mg daily QD compared to placebo on remission of SLE arthritis and/or rash in patients with SLE receiving concomitant standard therapy ov...

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A Feasibility study of Pemetrexed single agent and folic acid given as neoadjuvant treatment in patients with resectable rectal cancer To evaluate the feasibility of three neo-adjuvant cycles of single agent Pemetrexed at 500 mg/m2 q3w prior to surgery with or without radiotherapy in patients with resectable rectal cancer.

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