Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Mild Alzheimer's Patients This study will evaluate the safety and tolerability of repeated subcutaneous injections of CAD106 in patients with mild Alzheimer's disease.

• Country None
• organs None
• Specialty None

Long-term Safety, Tolerability and Efficacy of Omalizumab in Japanese Children To assess the long-term safety and tolerability of omalizumab by measuring AEs, serious AEs, physical examination, medical history, laboratory assessments and vital signs

• Country None
• organs None
• Specialty None

A 2-year randomized, multicenter, double-blind, placebocontrolled study to determine the efficacy and safety of intravenous zoledronic acid 5 mg administered either annually at randomization and 12 months, or administered at randomization only in the prevention of bone loss in postmenopausal women with osteopenia - To demonstrate that zoledronic acid 5 mg i.v. given annually at randomization and Month 12 is superior to placebo in percent change of BMD at the lumbar spine at Month 24 relative to baseline in Str...

• Country None
• organs None
• Specialty None

IBS-C Study A2306 Not provided at time of registration

• Country United States
• organs None
• Specialty None

Dose Ranging Study of Indacaterol in Japanese Patients With Chronic Obstructive Pulmonary Disease (COPD) The study was designed to obtain data about the efficacy and safety of 3 doses of indacaterol (150, 300, and 600 µg) in Japanese patients with chronic obstructive pulmonary disease (COPD) ...

• Country None
• organs None
• Specialty None

Efficacy in Reducing Fractures and Safety of Zoledronic Acid in Men With Osteoporosis This study will investigate if the drug zoledronic acid given once yearly is safe and has beneficial effects in treating osteoporosis by reducing bone loss and fractures in men with osteop...

• Country None
• organs None
• Specialty None

The impact of omalizumab treatment in UK clinical practice for asthma Background and study aims Allergic asthma is the most common type of asthma, where symptoms such as coughing, wheezing, chest tightness and breathlessness begin when the body reacts to something it is...

• Country None
• organs None
• Specialty None

A one year open label, non comparative extension to a randomised, multicentre, phase II study to evaluate the asfety, tolerability, pharmacokinetics and effects on iron concentration of repeated doses of 5-10 mg/kg/day of ICL670 relative to deferoxamine in sickle cell disease patients with transfusional hemosiderosis Evaluate the long-term safety and tolerability profile of ICL670 in sickle cell disease patients with transfusional iron overload requiring chelation therapy

• Country None
• organs None
• Specialty None

Understanding the mechanism of the acute phase response following intravenous (IV) bisphosphonates and its prevention: a study of the effects of zoledronic acid and co-prescription with fluvastatin or placebo Not provided at time of registration

• Country None
• organs None
• Specialty None

Study of the impact of indacaterol on the individual lives and health status of patients with chronic obstructive pulmonary disease (COPD) Background and study aims Clinical studies provide useful information regarding both the safety and effectiveness of medicines, but clinical trial settings are not always as close to a real-world sett...

• Country None
• organs None
• Specialty None