Study to Evaluate the Efficacy, Safety and Tolerability of N1539 To determine the analgesic efficacy, duration of effect, and safety of single doses of N1539 in subjects undergoing open abdominal hysterectomy

• Country Georgia, Poland, Serbia
• organs None
• Specialty None

ANDES-AGI-1067 as a Novel Antidiabetic Agent Evaluation Study This double-blind, placebo-controlled, dose-finding study is designed to identify the lowest AGI-1067 dose that improves glycemic control as measured by HbA1c and fasting glucose in subjec...

• Country Bosnia and Herzegovina, Former Serbia and Montenegro, Georgia, India, Macedonia, the former Yugoslav Republic of, South Africa, Ukraine, United States
• organs None
• Specialty None

Safety, Efficacy and Pharmacokinetics Study of ALD518 in Patients With Active Rheumatoid Arthritis The purpose of this study is to determine the safety and efficacy of ALD518 in three different doses in patients who have not had an adequate response to methotrexate.

• Country Canada, Georgia, India, Poland, Russian Federation, Serbia
• organs None
• Specialty None

A Multicenter Assessment of ALD403 in Frequent Episodic Migraine The purpose of this study is to assess ALD403 in the prevention of migraine headache in frequent episodic migraineurs.

• Country Georgia, United States
• organs None
• Specialty None

Evaluation of Patiromer in Heart Failure Patients The purpose of this study was to assess the effects of patiromer on serum potassium participants with heart failure. This study also assessed the safety and tolerability of patiromer in pa...

• Country Czech Republic, Georgia, Germany, Poland, Russian Federation, Ukraine, United States
• organs None
• Specialty None

Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in Subject Undergoing Hemorrhoidectomy Phase 2 study to evaluate three dose levels of SKY0402 compared with 75 mg of bupivacaine HCl.

• Country Georgia, United States
• organs None
• Specialty None

Pharmacokinetic Study of Tesmilifene (YMB1002) Plus Epirubicin and Cyclophosphamide in Metastatic Breast Cancer This is a Phase I, multi-centre, open-label, cross-over pharmacokinetic study designed to investigate whether the co-administration of a fixed dose of tesmilifene alters the plasma pharmac...

• Country Georgia, Russian Federation, Ukraine
• organs None
• Specialty None

A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL) The purpose of this study was to evaluate the efficacy and safety of patiromer (investigational drug) in the treatment of hyperkalemia (high serum potassium). The study also evaluated the ...

• Country Croatia, Czech Republic, Denmark, Georgia, Hungary, Italy, Serbia, Slovenia, Ukraine, United States
• organs None
• Specialty None

Evaluation of Patiromer Titration in Heart Failure Patients With Chronic Kidney Disease The purpose of this study was to evaluate the feasibility of individualized titration of patiromer according to serum potassium. This study also assessed the safety and tolerability of pat...

• Country Georgia, Slovenia
• organs None
• Specialty None

FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes The objective of this study is to evaluate the safety and efficacy of A 002 when added to high dose atorvastatin in subjects with an acute coronary syndrome (ACS)

• Country Georgia, Russian Federation, Ukraine
• organs None
• Specialty None