Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment To characterize the safety, tolerability, pharmacokinetics and immunogenicity of anetumab ravtansine in subjects with advanced solid cancers and with different degrees of hepatic or renal ...

• Country France, Moldova, Republic of
• organs None
• Specialty None

A Study of JNJ-40411813 as Supplementary Treatment to an Antidepressant in Adults With Depression and Anxiety Symptoms The purpose of this study is to evaluate the efficacy and overall safety and tolerability of treatment with adjunctive JNJ-40411813 compared to placebo in patients with MDD with anxiety sy...

• Country Bulgaria, Hungary, Moldova, Republic of, Romania, Russian Federation, Ukraine
• organs None
• Specialty None

Phase IIb-III Study of BL-1020 Small Molecule for Schizophrenia This is a randomized, double-blind, active-controlled, 6 month study designed to evaluate the cognitive effects of treatment with CYP-1020 compared to risperidone. The primary efficacy end...

• Country India, Moldova, Republic of, Romania
• organs None
• Specialty None

CAPRIVI: Community Acquired Pneumonia: Treatment With Avelox® in Hospitalized Patients The aim of this study is to obtain data from hospitalized Community Acquired Pneumonia (CAP) patients on the disease including disease severity, clinical signs and symptoms and measures us...

• Country Croatia, France, Hungary, Jordan, Kazakhstan, Lebanon, Macedonia, the former Yugoslav Republic of, Moldova, Republic of, Romania, Russian Federation, Ukraine
• organs None
• Specialty None

A Phase 2a, Dose-Ranging Study to Evaluate the Safety, Pharmacokinetics and Efficacy of VX-135 With Ribavirin in Treatment-Naïve Subjects With Chronic Hepatitis C The purpose of the study is to determine the safety, pharmacokinetics and efficacy of orally administered VX-135 with ribavirin in treatment naive subjects with chronic hepatitis C infecti...

• Country Moldova, Republic of
• organs None
• Specialty None

A Study to Assess the Safety of a Potential New Drug in Comparison to the Standard Practice of Dosing With Warfarin for Non-valvular Atrial Fibrillation This study is to assess the safety of a potential new drug DU-176b for the prevention of stroke/systemic embolic event (SEE) in individuals with non-valvular atrial fibrillation (AF). The ...

• Country Belarus, Belgium, Bosnia and Herzegovina, Canada, Chile, Latvia, Mexico, Moldova, Republic of, Russian Federation, Slovakia, Ukraine, United States
• organs None
• Specialty None

Evaluation of CLP in Heart Failure Patients With Chronic Kidney Disease The purpose of this study is to determine the effects of CLP on serum potassium and signs and symptoms of fluid overload in heart failure patients with chronic kidney disease.

• Country Armenia, Georgia, Moldova, Republic of
• organs None
• Specialty None

A Multiple Dose Study Of PD-0360324 In Patients With Active Cutaneous Lupus Erythematosus This study is designed to evaluate the safety and tolerability of multiple intravenously administered doses of PD-0360324 in patients with cutaneous lupus erythematosus. Changes in disease...

• Country Canada, Moldova, Republic of, United States
• organs None
• Specialty None

Sarilumab Effect on the Pharmacokinetics of Simvastatin Primary Objective: To evaluate the effect of a single 200 mg subcutaneous injection of sarilumab on the pharmacokinetics of simvastatin in patients with rheumatoid arthritis Second...

• Country Korea, Republic of, Moldova, Republic of, United States
• organs None
• Specialty None

RP5063 in Subjects With Schizophrenia or Schizoaffective Disorder The objective of this study is to evaluate the efficacy and safety of RP5063 relative to placebo for the treatment of schizophrenia or schizoaffective disorder.

• Country India, Malaysia, Moldova, Republic of, Philippines, United States
• organs None
• Specialty None