A single arm, open-label, phase II study to assess the efficacy of rucaparib in metastatic breast cancer patients with a BRCAness genomic signature

Update Il y a 5 ans
Reference: EUCTR2015-000580-14

Woman Man

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Extract

To assess the clinical benefit rate with rucaparib in previously treated patients with metastatic breast cancer with BRCAness profile (defined by Clovis genomic signature), and if it is significant, to assess the overall response rate.


Inclusion criteria

  • Patients with progressing metastatic breast cancer pretreated with at least one line of chemotherapy at the metastatic setting

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