Genetic Linkage Study of Idiopathic Talipes Equinovarus (ITEV) (Clubfoot)

Update Il y a 4 ans
Reference: NCT00474344

Woman and Man

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Extract

The goal of this study is to identify and characterize the genetic loci causing idiopathic talipes equinovarus (clubfoot). The hypothesis is that a few genes account for a substantial fraction of ITEV and that these genes can be identified in defined populations. Towards this goal, in preliminary studies, Dr. Hecht's group has identified two genes, NAT2 and CASP10, which demonstrate evidence for linkage and association to ITEV.


Inclusion criteria

  • Clubfoot

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