A Randomized Trial of Temsirolimus versus Sorafenib as Second-Line Therapy in Patients With Advanced Renal Cell Carcinoma Who Have Failed First-Line Sunitinib Therapy

Mise à jour : Il y a 4 ans
Référence : EUCTR2007-000062-20

Femme et Homme

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Extrait

To compare the safety and tolerability of temsirolimus and sorafenib when used as single agents in the second-line setting in subjects with advanced RCC who have failed prior first-line treatment with sunitinib due to progressive disease (PD). To compare the efficacy, as measured by PFS (determined by a centralized independent assessment), of temsirolimus and sorafenib when used as single agents in the second-line setting in subjects with advanced RCC who have failed prior first-line treatment with sunitinib.


Critère d'inclusion

  • Patients With Advanced Renal Cell Carcinoma Who Have Failed First-Line Sunitinib Therapy