Woman and Man
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Extract
The primary objective of this study is to test the hypothesis that exenatide injected twice daily is non-inferior to glimepiride given once daily before breakfast (titrated up to the maximally tolerated dose) in terms of time to treatment failure (TTF), when given as addon treatment to patients with type 2 diabetes and BMI levels of ≥ 25 kg/m2 who failed to achieve glycemic control with metformin alone. ----Study period III----- to explore the effects of different treatment options in patients with type 2 diabetes who failed to achieve HbA1c targets with metformin plus exenatide or plus glimepiride
Inclusion criteria
- Type 2 diabetes mellitus