Study to Assess the Long-term Safety, Tolerability, and Efficacy of AMG 827 in Subjects With Psoriasis

Update Il y a 4 ans
Reference: EUCTR2009-016163-12

Woman and Man

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Extract

To evaluate the safety of long-term exposure with AMG 827 in subjects with moderate to severe psoriasis. To evaluate the efficacy of AMG 827 as measured by the following: − The proportion of subjects with a static physician’s global assessment (sPGA) of clear (0) or clear/almost clear (0 or 1) − Percent improvement in Psoriasis Area and Severity Index (PASI) − The proportion of subjects with a 50% improvement in PASI (PASI 50), PASI 75, PASI 90, and PASI 100 − Body surface area (BSA) involvement


Inclusion criteria

  • Moderate to Severe Plaque Psoriasis

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